"BMP7" Related Products

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Recombinant Human BMP7, HIgG1 Fc-tagged, mutant

Cat.No. : BMP7-508H
Product Overview : The extracellular domain of human BMP-7 (NP_001710.1) (Arg292-Cys430) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
Description : The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity.
Source : CHO cells
Species : Human
Tag : HIgG1 Fc-tagged, mutant
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ability to induce alkaline phosphatase production.
Molecular Mass : 42KDa (monomer)
AA Sequence : Arg292-Cys430
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : BMP7 bone morphogenetic protein 7 [ Homo sapiens ]
Official Symbol : BMP7
Synonyms : BMP7; bone morphogenetic protein 7; OP 1; osteogenic protein 1; BMP-7; OP-1;
Gene ID : 655
mRNA Refseq : NM_001719
Protein Refseq : NP_001710
MIM : 112267
UniProt ID : P18075
Chromosome Location : 20q13
Pathway : ALK2 signaling events, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem; Hedgehog signaling pathway, organism-specific biosystem; Hedgehog signaling pathway, conserved biosystem;
Function : cytokine activity; growth factor activity; protein binding; contributes_to protein binding;

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