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Recombinant Mouse CD86, MIgG2a Fc-tagged

Cat.No.: CD86-365M
Product Overview: The extracellular domain of mouse CD86 [B7-2] (NP_062261.3) (Val26-Glu245) is fused to the N-terminus of the Fc region of mouse IgG2a.
Source: CHO cells
Species: Mouse
Tag: MIgG2a Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to induce IL-2 secretion by Jurkat human acute T cell leukemia cells.
Molecular Mass: 51 KDa (monomer)
AA Sequence: Val26-Glu245
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: Cd86 CD86 antigen [ Mus musculus ]
Official Symbol: CD86
Synonyms: CD86; CD86 antigen; T-lymphocyte activation antigen CD86; activation B7-2 antigen; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS/A-2;
Gene ID: 12524
mRNA Refseq: NM_019388
Protein Refseq: NP_062261
Pathway: Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem;
Function: receptor activity; receptor binding;

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