Recombinant Human MAPK3

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Recombinant Human MAPK3

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Cat.No. : MAPK3-36H
Product Overview : Recombinant full-length tag-free human ERK1 was expressed in E. coli cells.
Description : The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Source : E.Coli
Species : Human
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Molecular Mass : ~44 kDa
Purity : >90%
Applications : Kinase Assay; Western Blot
Storage : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.2 ug/ul
Gene Name : MAPK3 mitogen-activated protein kinase 3 [ Homo sapiens (human) ]
Official Symbol : MAPK3
Synonyms : MAPK3; mitogen-activated protein kinase 3; ERK1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; MGC20180; EC 2.7.11.24; Extracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase 1; Microtubule-associated protein 2 kinas; OTTHUMP00000174538; OTTHUMP00000174540; Microtubule-associated protein 2 kinase
Gene ID : 5595
mRNA Refseq : NM_002746
Protein Refseq : NP_002737
MIM : 601795
UniProt ID : P27361
Chromosome Location : 16p11.2
Pathway : AGE/RAGE pathway; ALK1 signaling events; ATF-2 transcription factor network
Function : ATP binding; MAP kinase activity; phosphatase binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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