Recombinant Human MTHFD2, GST-tagged
Cat.No. : | MTHFD2-395H |
Product Overview : | Recombinant Human MTHFD2 (16 a.a. - 344 a.a.), fused with GST-tag at N-terminal, was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 61.93 kDa |
AA Sequence : | SLRLRPFHLAAVRNEAVVISGRKLA QQIKQEVRQEVEEWVASGNKRPHLS VILVGENPASHSYVLNKTRAAAVVG INSETIMKPASISEEELLNLINKLN NDDNVDGLLVQLPLPEHIDERRICN AVSPDKDVDGFHVINVGRMCLDQYS MLPATPWGVWEIIKRTGIPTLGKNV VVAGRSKNVGMPIAMLLHTDGAHER PGGDATVTISHRYTPKEQLKKHTIL ADIVISAAGIPNLITADMIKEGAAV IDVGINRVHDPVTAKPKLVGDVDFE GVRQKAGYITPVPGGVGPMTVAMLM KNTIIAAKKVLRLEEREVLKSKELG VATN |
Applications : | ELSA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [ Homo sapiens ] |
Official Symbol : | MTHFD2 |
Synonyms : | MTHFD2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; NMDMC; methylenetetrahydrofolate dehydrogenase 2; NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase; EC 1.5.1.15 |
Gene ID : | 10797 |
mRNA Refseq : | NM_006636 |
Protein Refseq : | NP_006627 |
MIM : | 604887 |
UniProt ID : | P13995 |
Chromosome Location : | 2p13.1 |
Pathway : | C1-unit interconversion; Nucleotide Metabolism; One carbon pool by folate; tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate |
Function : | NOT formate-tetrahydrofolate ligase activity; magnesium ion binding; methenyltetrahydrofolate cyclohydrolase activity |
Products Types
◆ Recombinant Protein | ||
MTHFD2-5779M | Recombinant Mouse MTHFD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mthfd2-4210M | Recombinant Mouse Mthfd2 Protein, Myc/DDK-tagged | +Inquiry |
MTHFD2-22H | Recombinant Human MTHFD2 protein, his-tagged | +Inquiry |
MTHFD2-1868B | Recombinant Bovine MTHFD2 Protein (36-350 aa), His-SUMO-tagged | +Inquiry |
MTHFD2-571H | Recombinant Human MTHFD2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
MTHFD2-4082HCL | Recombinant Human MTHFD2 293 Cell Lysate | +Inquiry |
MTHFD2-4083HCL | Recombinant Human MTHFD2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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