Recombinant Human C1S 293 Cell Lysate
Cat.No. : | C1S-8131HCL |
- Specification
- Gene Information
- Related Products
Description : | Antigen standard for complement component 1, s subcomponent (C1S), transcript variant 2 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
Source : | HEK 293 cells |
Species : | Human |
Components : | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
Size : | 0.1 mg |
Storage Instruction : | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment. |
Applications : | ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane. |
Gene Name : | C1S complement component 1, s subcomponent [ Homo sapiens ] |
Official Symbol : | C1S |
Synonyms : | C1S; complement component 1, s subcomponent; complement C1s subcomponent; C1 esterase; basic proline-rich peptide IB-1; complement component 1 subcomponent s; FLJ44757; |
Gene ID : | 716 |
mRNA Refseq : | NM_001734 |
Protein Refseq : | NP_001725 |
MIM : | 120580 |
UniProt ID : | P09871 |
Chromosome Location : | 12p13 |
Pathway : | Classical antibody-mediated complement activation, organism-specific biosystem; Complement Activation, Classical Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem; |
Function : | calcium ion binding; peptidase activity; serine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
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C1S-2572H | Recombinant Human C1S Protein, His (Fc)-Avi-tagged | +Inquiry |
C1S-597H | Recombinant Human C1s protein, His-tagged | +Inquiry |
C1S-5143H | Recombinant Human C1S Protein (Met1-Asp688), C-His tagged | +Inquiry |
C1S-26615TH | Recombinant Human C1S | +Inquiry |
◆ Native Protein | ||
C1S-550H | Active Native Human C1S Enzyme | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (5)
Ask a questionYes, C1S protein deficiency is rare, but it is more common in patients with a family history of HAE.
Side effects can include infusion site reactions or hypersensitivity reactions, so treatment is typically administered under medical supervision.
C1S protein replacement therapy is usually given intravenously, and the frequency of administration may vary depending on the patient's needs.
C1S replacement therapy is primarily used for HAE, but researchers are investigating its potential use in other complement-related disorders.
Yes, ongoing research aims to better understand the role of C1S in HAE and explore new treatment options, such as gene therapy.
Customer Reviews (3)
Write a reviewThis level of sensitivity and specificity has streamlined my research and allowed for precise protein characterization.
The protein bands detected were exceptionally distinct, enabling easy interpretation and accurate analysis of protein expression patterns.
To summarize, the C1S protein is a highly recommended asset for various research endeavors, including ELISA, protein electron microscopy structure analysis, and Western blotting.
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