Recombinant Human APLNR 293 Cell Lysate
Cat.No. : | APLNR-8791HCL |
- Specification
- Gene Information
- Related Products
Description : | Antigen standard for apelin receptor (APLNR), transcript variant 1 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
Source : | HEK 293 cells |
Species : | Human |
Components : | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
Size : | 0.1 mg |
Storage Instruction : | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment. |
Applications : | ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane. |
Gene Name : | APLNR apelin receptor [ Homo sapiens ] |
Official Symbol : | APLNR |
Synonyms : | APLNR; apelin receptor; AGTRL1, angiotensin II receptor like 1; APJ; APJ (apelin) receptor; APJR; FLJ90771; APJ receptor; HG11 orphan receptor; angiotensin receptor-like 1; G protein-coupled receptor APJ; G-protein coupled receptor APJ; angiotensin II receptor-like 1; G-protein coupled receptor HG11; HG11; AGTRL1; FLJ96609; MGC45246; |
Gene ID : | 187 |
mRNA Refseq : | NM_005161 |
Protein Refseq : | NP_005152 |
MIM : | 600052 |
UniProt ID : | P35414 |
Chromosome Location : | 11q12.1 |
Pathway : | Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem; |
Function : | G-protein coupled receptor activity; receptor activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
APLNR-371R | Recombinant Rat APLNR Protein, His (Fc)-Avi-tagged | +Inquiry |
APLNR-356H | Recombinant Human APLNR Protein, His (Fc)-Avi-tagged | +Inquiry |
APLNR-187R | Recombinant Rhesus Macaque APLNR Protein, His (Fc)-Avi-tagged | +Inquiry |
APLNR-0967H | Recombinant Human APLNR Protein (M1-R330), Flag, His tagged | +Inquiry |
APLNR-358R | Recombinant Rhesus monkey APLNR Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (20)
Ask a questionAt present, there is no specific optimal treatment time, which needs to be determined according to the specific situation and condition of the patient.
At present, there are no clear results of long-lasting efficacy studies, and more long-term clinical observations and studies are needed.
As with all drugs, there are risks and side effects associated with the use of APLNR s, such as allergic reactions and bleeding.
There is no clear way to prevent use, and more research and exploration is needed.
According to studies, APLNR can raise HDL cholesterol levels and lower LDL cholesterol levels, thus affecting lipid levels.
Studies have shown that the recombinant APLNR protein is not immunogenic in most people.
At present, there are no relevant studies to prove whether APLNR is effective in the treatment of children, and more research and exploration are needed.
According to research, APLNR may increase the therapeutic effect by regulating its own repair mechanism.
Treatment effectiveness may vary and needs to be evaluated on a patient basis.
Recombinant APLNR proteins can be expressed in microorganisms such as Escherichia coli using genetic engineering technology, and then extracted and purified by protein purification technology.
Yes, there are currently clinical trials underway to evaluate the safety and efficacy of APLNR.
Current studies have shown that APLNR has a potential role in the treatment of diseases such as heart disease, hepatitis, tumors and kidney disease.
According to research, recombinant APLNR may be more effective in the treatment of the elderly.
The therapeutic effect and targeting mechanism of APLNR is mainly through binding to its receptor APJ and activating related signaling pathways.
There is no specific standard dose, and the dosage is usually determined based on patient conditions and clinical trial results.
At present, there are no specific studies to show whether the long-term use of APLNR is safe and effective, and long-term clinical observation is needed.
According to research, the combination of APLNR and other drugs may produce a more significant effect.
Based on current research and clinical trials, APLNR s are more expensive, and more research and production are needed to reduce costs.
At present, there is no detailed evidence that APLNR can completely replace traditional drug therapy, and more research and exploration are needed.
There is currently no specific method of oral administration, but relevant studies may be explored.
Customer Reviews (4)
Write a reviewAPLNR is stable under various experimental conditions and is ideal for a variety of application scenarios.
Green production process of APLNR has the characteristics of high efficiency and environmental protection, and has set a new benchmark for the industry.
The quantitative accuracy of Western blot is very high, which can accurately determine the content of target protein, indicating that it has high accuracy and low error rate.
Stability of APLNR is very good, and it can be carried out for long periods of experimental operation without worrying about changes and effects of its performance.
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