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Recombinant Human AGPAT1 cell lysate

Cat.No. : AGPAT1-36HCL
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) [ Homo sapiens ]
Official Symbol : AGPAT1
Synonyms : AGPAT1; 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha); 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; LPAAT alpha; 1-AGPAT 1; 1-AGP acyltransferase 1; lysophospholipid acyltransferase; lysophosphatidic acid acyltransferase alpha; 1-acylglycerol-3-phosphate O-acyltransferase 1 (acetoacetly Coenzyme A thiolase); G15; LPAATA; 1-AGPAT1; LPAAT-alpha; MGC4007; MGC5423;
Gene ID : 10554
mRNA Refseq : NM_006411
Protein Refseq : NP_006402
MIM : 603099
UniProt ID : Q99943
Chromosome Location : 6p21.3
Pathway : CDP-diacylglycerol biosynthesis I, organism-specific biosystem; CDP-diacylglycerol biosynthesis I, conserved biosystem; ChREBP activates metabolic gene expression, organism-specific biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem;
Function : 1-acylglycerol-3-phosphate O-acyltransferase activity; transferase activity, transferring acyl groups;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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What’s the role of AGPAT1 in lipid metabolism 12/20/2022

AGPAT1 catalyzes the acylation of glycerol-3-phosphate, a key step in phospholipid synthesis.

Is AGPAT1 essential for normal cellular function 12/03/2022

Yes, AGPAT1 is essential for proper lipid metabolism and cellular membrane synthesis.

How does AGPAT1’s role intersect with phospholipid remodeling 10/29/2022

AGPAT1 contributes to phospholipid biosynthesis and remodeling pathways.

How does AGPAT1’s function relate to insulin sensitivity 07/18/2022

AGPAT1’s activity is linked to insulin sensitivity and glucose metabolism.

How does AGPAT1’s role affect energy storage and utilization 03/11/2022

AGPAT1’s involvement in lipid metabolism influences energy storage and utilization.

Can AGPAT1’s dysfunction lead to metabolic disorders 12/11/2021

Yes, AGPAT1 mutations can result in metabolic disorders and lipodystrophic phenotypes.

Can AGPAT1’s activity influence cellular response to stress 07/27/2021

Yes, AGPAT1’s function can be influenced by cellular stress and metabolic challenges.

How does AGPAT1 participate in glycerolipid synthesis 04/01/2021

AGPAT1 adds fatty acids to glycerol-3-phosphate, producing lysophosphatidic acid (LPA).

Can AGPAT1 be targeted for therapeutic interventions 01/04/2021

Yes, AGPAT1 is a potential target for modulating lipid metabolism in metabolic disorders.

Can AGPAT1 impact adipocyte differentiation 12/02/2020

Yes, AGPAT1’s activity is linked to adipocyte differentiation and fat cell formation.

How is AGPAT1’s connection to lipogenesis studied 10/29/2020

Research investigates AGPAT1’s contribution to de novo lipogenesis and fatty acid synthesis.

How is AGPAT1’s involvement in glycerophospholipid metabolism studied 12/07/2019

Research investigates AGPAT1’s role in lipid biosynthesis pathways.

Can AGPAT1 contribute to the regulation of lipid droplet formation 04/19/2019

Yes, AGPAT1’s role can impact the formation and turnover of lipid droplets.

Can AGPAT1 play a role in membrane fusion processes 12/10/2018

Yes, AGPAT1’s involvement in lipid synthesis can influence membrane fusion and trafficking.

How is AGPAT1’s role in triglyceride synthesis studied 07/12/2018

Research explores AGPAT1’s involvement in triglyceride synthesis and energy storage.

Can AGPAT1’s function be regulated by post-translational modifications 12/25/2017

Yes, post-translational modifications can modulate AGPAT1’s activity.

Can AGPAT1’s activity affect cellular membranes 09/09/2017

Yes, AGPAT1’s function contributes to the composition of cellular membranes and lipid homeostasis.

How is AGPAT1’s role in lipid composition of tissues studied 08/01/2016

Research explores how AGPAT1 affects the lipid composition of different tissues.

How does AGPAT1’s function relate to lipodystrophy 05/24/2016

Mutations in AGPAT1 can cause lipodystrophy, a disorder affecting fat tissue distribution.

How is AGPAT1’s role connected to glycerolipid biosynthesis? 01/18/2016

AGPAT1’s function is a critical step in the biosynthesis of glycerolipids like phosphatidic acid.

Customer Reviews (5)

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Reviews
02/28/2019

     Consistently achieving specific outcomes validated the crucial role of the product in our studies.

    08/19/2018

       Comprehensive documentation streamlined our incorporation of the product into our research workflow.

      07/21/2017

         The product’s distinct features advanced our research into uncharted territories.

        07/05/2017

           Despite its cost, the insights gained from the product’s usage made it a worthy investment.

          01/16/2016

             The observed changes in cell morphology were directly attributed to the product’s effectiveness.

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