Recombinant Human AGPAT1 cell lysate
Cat.No. : | AGPAT1-36HCL |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) [ Homo sapiens ] |
Official Symbol : | AGPAT1 |
Synonyms : | AGPAT1; 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha); 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; LPAAT alpha; 1-AGPAT 1; 1-AGP acyltransferase 1; lysophospholipid acyltransferase; lysophosphatidic acid acyltransferase alpha; 1-acylglycerol-3-phosphate O-acyltransferase 1 (acetoacetly Coenzyme A thiolase); G15; LPAATA; 1-AGPAT1; LPAAT-alpha; MGC4007; MGC5423; |
Gene ID : | 10554 |
mRNA Refseq : | NM_006411 |
Protein Refseq : | NP_006402 |
MIM : | 603099 |
UniProt ID : | Q99943 |
Chromosome Location : | 6p21.3 |
Pathway : | CDP-diacylglycerol biosynthesis I, organism-specific biosystem; CDP-diacylglycerol biosynthesis I, conserved biosystem; ChREBP activates metabolic gene expression, organism-specific biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem; |
Function : | 1-acylglycerol-3-phosphate O-acyltransferase activity; transferase activity, transferring acyl groups; |
Products Types
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (20)
Ask a questionAGPAT1 catalyzes the acylation of glycerol-3-phosphate, a key step in phospholipid synthesis.
Yes, AGPAT1 is essential for proper lipid metabolism and cellular membrane synthesis.
AGPAT1 contributes to phospholipid biosynthesis and remodeling pathways.
AGPAT1’s activity is linked to insulin sensitivity and glucose metabolism.
AGPAT1’s involvement in lipid metabolism influences energy storage and utilization.
Yes, AGPAT1 mutations can result in metabolic disorders and lipodystrophic phenotypes.
Yes, AGPAT1’s function can be influenced by cellular stress and metabolic challenges.
AGPAT1 adds fatty acids to glycerol-3-phosphate, producing lysophosphatidic acid (LPA).
Yes, AGPAT1 is a potential target for modulating lipid metabolism in metabolic disorders.
Yes, AGPAT1’s activity is linked to adipocyte differentiation and fat cell formation.
Research investigates AGPAT1’s contribution to de novo lipogenesis and fatty acid synthesis.
Research investigates AGPAT1’s role in lipid biosynthesis pathways.
Yes, AGPAT1’s role can impact the formation and turnover of lipid droplets.
Yes, AGPAT1’s involvement in lipid synthesis can influence membrane fusion and trafficking.
Research explores AGPAT1’s involvement in triglyceride synthesis and energy storage.
Yes, post-translational modifications can modulate AGPAT1’s activity.
Yes, AGPAT1’s function contributes to the composition of cellular membranes and lipid homeostasis.
Research explores how AGPAT1 affects the lipid composition of different tissues.
Mutations in AGPAT1 can cause lipodystrophy, a disorder affecting fat tissue distribution.
AGPAT1’s function is a critical step in the biosynthesis of glycerolipids like phosphatidic acid.
Customer Reviews (5)
Write a reviewConsistently achieving specific outcomes validated the crucial role of the product in our studies.
Comprehensive documentation streamlined our incorporation of the product into our research workflow.
The product’s distinct features advanced our research into uncharted territories.
Despite its cost, the insights gained from the product’s usage made it a worthy investment.
The observed changes in cell morphology were directly attributed to the product’s effectiveness.
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