"GRB10" Related Products

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Recombinant Human GRB10 cell lysate

Cat.No.: GRB10-751HCL
Description: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: GRB10 growth factor receptor-bound protein 10 [ Homo sapiens ]
Official Symbol: GRB10
Synonyms: GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207;
Gene ID: 2887
mRNA Refseq: NM_001001549
Protein Refseq: NP_001001549
MIM: 601523
UniProt ID: Q13322
Chromosome Location: 7p12.2
Pathway: EGFR1 Signaling Pathway, organism-specific biosystem; IGF1 pathway, organism-specific biosystem; Insulin Pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem; Kit Receptor Signaling Pathway, organism-specific biosystem; PDGFR-beta signaling pathway, organism-specific biosystem;
Function: SH3/SH2 adaptor activity; insulin receptor binding; protein binding;

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