Recombinant Human STK10 cell lysate

• Cat.No.: STK10-1711HCL

Specification

• Description: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: STK10 serine/threonine kinase 10 [ Homo sapiens ]
• Official Symbol: STK10
• Synonyms: STK10; serine/threonine kinase 10; serine/threonine-protein kinase 10; LOK; PRO2729; lymphocyte-oriented kinase
• Gene ID: 6793
• mRNA Refseq: NM_005990
• Protein Refseq: NP_005981
• MIM: 603919
• UniProt ID: O94804
• Chromosome Location: 5q35.1
• Function: ATP binding; nucleotide binding; polo kinase kinase activity; protein binding; protein homodimerization activity; protein serine/threonine kinase activity