"TYK2" Related Products

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Recombinant Human TYK2 cell lysate

Cat.No. : TYK2-1867HCL
Description : This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : TYK2 tyrosine kinase 2 [ Homo sapiens ]
Official Symbol : TYK2
Synonyms : TYK2; tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; JTK1;
Gene ID : 7297
mRNA Refseq : NM_003331
Protein Refseq : NP_003322
MIM : 176941
UniProt ID : P29597
Chromosome Location : 19p13.2
Pathway : Cytokine Signaling in Immune system, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; IL-3 Signaling Pathway, organism-specific biosystem; IL-4 signaling Pathway, organism-specific biosystem;
Function : ATP binding; growth hormone receptor binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein tyrosine kinase activity;

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