Active Recombinant Mouse Pim3, GST-tagged

• Cat.No.: Pim3-1081M
• Product Overview: Recombinant full-length mouse PIM3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Mouse
• Source: Sf9 Cells
• Tag: GST
• Protein Length: Full Length
• Description: PIM3 or pim-3 oncogene belongs to a family of protooncogenes that encode serine/threonine protein kinases. Pim-3 expressed in hepatocellular carcinoma development and plays a main role in the proliferation of human hepatoma cell lines. Pim-3 also expressed in human pancreatic cancer cell and phosphorylates BAD to block Bad-mediated apoptosis in human pancreatic cancer cell lines.
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: 785 nmol/min/mg
• Molecular Mass: ~63 kDa
• Purity: >90%
• Applications: Kinase Assay; Western Blot
• Stability: 1 yr at -70oC from date of shipment.
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/ul

Gene Information

• Gene Name: Pim3?proviral integration site 3 [?Mus musculus?(house mouse) ]
• Official Symbol: Pim3
• Synonyms: Pim3; proviral integration site 3; Kid1; BC026639; serine/threonine-protein kinase pim-3; KID-1/kinase induced by depolarization; NP_663453.1; EC 2.7.11.1
• Gene ID: 223775
• mRNA Refseq: NM_145478
• Protein Refseq: NP_663453
• UniProt ID: P58750
• Chromosome Location: 15 E3; 15
• Function: ATP binding; kinase activity; protein binding; protein serine/threonine kinase activity