Recombinant Cynomolgus CD3E&CD3D, His & flag-tagged
| Cat.No. : | CD3E&CD3D-187C |
| Product Overview : | Recombinant Cynomolgus CD3E & CD3D heterodimer protein (Cynomolgus CD3E & CD3D heterodimer) Gln 22 - Asp 117 (CD3E,Q95LI5) & Phe 22 - Ala 105 (CD3D,Q95LI8) was produced in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
| Description : | T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. |
| Source : | HEK293 |
| Species : | Cynomolgus |
| Tag : | His & flag |
| Predicted N Terminal : | Gln 22 (CD3E) and Phe 22 (CD3D) |
| Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
| Molecular Mass : | The heterodimer Cynomolgus CD3E & CD3D heterodimer is produced by co-expression of CD3E and CD3D, has a calculated MW of 15.5 kDa (CD3E) and 14.5 kDa (CD3D). Subunit CD3E is fused with his tag at the C-terminus and subunit CD3D is fused with flag tag at t |
| Endotoxin : | Less than 1.0 EU per μg of the Cynomolgus CD3E & CD3D heterodimer by the LAL method. |
| Purity : | >92% as determined by SDS-PAGE. |
| Applications : | CD Antigens |
| Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC). |
| Gene Name : | CD3E?CD3e molecule, epsilon (CD3-TCR complex) [?Macaca fascicularis?(crab-eating macaque) ] |
| Official Symbol : | CD3E |
| Synonyms : | CD3E; CD3e molecule, epsilon (CD3-TCR complex); T-cell surface glycoprotein CD3 epsilon chain; CD3 epsilon FN18+; CD3 epsilon FN18- |
| Gene ID : | 102133065 |
| mRNA Refseq : | NM_001283615 |
| Protein Refseq : | NP_001270544 |
| UniProt ID : | Q95LI5 |
| Chromosome Location : | 14 |
| Pathway : | Chagas disease (American trypanosomiasis); Hematopoietic cell lineage; Primary immunodeficiency |
Products Types
| ◆ Lysates | ||
| CD3E-1275HCL | Recombinant Human CD3E cell lysate | +Inquiry |
| CD3E-1602CCL | Recombinant Cynomolgus CD3E cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket
