Active Recombinant Human FGF2
Cat.No. : | FGF2-12H |
Product Overview : | Recombinant Human Fibroblast Growth Factor Basic is produced with our E. coli expression system. The target protein is expressed with sequence (Gly132-Ser288) of Human FGF basic. |
- Specification
- Gene Information
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Description : | FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family.The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a 0.2 μM filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5. |
Bio-activity : | >2.0 x 10^6 U/mg |
Endotoxin : | Less than 0.1 EU/μg. |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at< -20°c, though stable at room temperature for 3>Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at< -20°c for 3> |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 1X PBS.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | FGF2 fibroblast growth factor 2 (basic) [ Homo sapiens ] |
Official Symbol : | FGF2 |
Synonyms : | FGF2; fibroblast growth factor 2 (basic); FGFB; fibroblast growth factor 2; prostatropin; heparin-binding growth factor 2; basic fibroblast growth factor bFGF; BFGF; FGF-2; HBGF-2; |
Gene ID : | 2247 |
mRNA Refseq : | NM_002006 |
Protein Refseq : | NP_001997 |
MIM : | 134920 |
UniProt ID : | P09038 |
Chromosome Location : | 4q26 |
Pathway : | Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1b ligand binding and activation, organism-specific biosystem; FGFR1c ligand binding and activation, organism-specific biosystem; |
Function : | chemoattractant activity; cytokine activity; fibroblast growth factor binding; fibroblast growth factor receptor binding; growth factor activity; heparin binding; ligand-dependent nuclear receptor transcription coactivator activity; protein binding; protein tyrosine kinase activity; voltage-gated calcium channel activity; |
Products Types
◆ Recombinant Protein | ||
FGF2-402F | Active Recombinant Human FGF2 Protein (145 aa) | +Inquiry |
Fgf2-79M | Recombinant Active Mouse FGF2 Protein, His-tagged(N-ter) | +Inquiry |
FGF2-12B | Recombinant Bovine FGF2 Protein | +Inquiry |
Fgf2-398F | Active Recombinant Mouse Fgf2 Protein (146 aa) | +Inquiry |
FGF2-401F | Active Recombinant Human FGF2 Protein (146 aa) | +Inquiry |
◆ Native Protein | ||
FGF2-34B | Active Native Bovine bFGF | +Inquiry |
◆ Lysates | ||
FGF2-638HCL | Recombinant Human FGF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionFGF2 promotes cell migration and angiogenesis and regulates bone homeostatic balance.
FGF2 is widely expressed in the nervous system.
FGF2 is mainly expressed in tissues such as mammary glands and ovaries of sheep.
FGF1 has a high degree of homology with FGF2.
FGF2 is involved in diseases such as cardiovascular disease, breast disease and bone homeostasis.
FGF2 negatively regulates bone homeostasis.
Customer Reviews (2)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The purchased protein is suitable for WB experiments and I am satisfied with the results.
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