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Recombinant Human RORC, GST-tagged

Cat.No.: RORC-114H
Product Overview: Recombinant Human GST-tagged RAR-related orphan receptor gamma ligand-binding domain (RORG-LBD) consists of a 218 a.a. GST tag, a 13 a.a. flexible linker and a 268 a.a. RORG-LBD, Acc# AAH31554.1, amino acids 251-518, was expressed in baculovirus-infected insect cells and purified using affinity chromatography.
Description: RAR-related orphan receptor gamma (RORγ or RORG) is also known as RORC as in humans is encoded by the RORC (RAR-related orphan receptor C) gene. It is a member of the nuclear receptor family of transcription factors, nuclear receptor subfamily 1, group F, member 3 (NR1F3).
Source: Sf9 insect cells
Species: Human
Tag: GST
Form: 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 0.5 mM EDTA, 3 mM Dithiothreitol, 7 mM reduced glutathione, 20% glycerol
Purity: >90%
Applications: Ligand binding and coactivator peptide recruitment assays.
Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.
Gene Name: RORC RAR-related orphan receptor C [ Homo sapiens ]
Official Symbol: RORC
Synonyms: RORC; RAR-related orphan receptor C; nuclear receptor ROR-gamma; NR1F3; RORG; RZRG; TOR; nuclear receptor RZR-gamma; retinoic acid-binding receptor gamma; retinoid-related orphan receptor gamma; RAR-related orphan receptor C, isoform a; RAR-related orphan nuclear receptor variant 2; nuclear receptor subfamily 1 group F member 3; RZR-GAMMA; MGC129539;
Gene ID: 6097
mRNA Refseq: NM_001001523
Protein Refseq: NP_001001523
MIM: 602943
UniProt ID: P51449
Chromosome Location: 1q21
Pathway: Circadian rhythm - mammal, organism-specific biosystem; Circadian rhythm - mammal, conserved biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem;
Function: DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; zinc ion binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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