Native Human C4b-Binding Protein

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Native Human C4b-Binding Protein

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Cat.No. : C4BPB-184H
Description : C4b-binding protein is a regulatory protein of the Complement Cascade that possesses decay-accelerating activity. Circulating in plasma, it aids in the control of fluid-phase and surface-associated activation of C3 and C5 and serves as a cofactor to Factor 1 in the proteolytic degradation of C4b. There are three isoforms circulating in plasma; 7 alpha chains and 1 Beta chain, 6 alpha chains and 1 Beta chain, and 7 alpha chains without a Beta chain. The 7 alpha, 1 Beta form is the most abundant. All C4BP molecules that contain a Beta chain circulate in plasma in a high-affinity, calcium-dependent complex with vitamin K-dependent, anticoagulant Protein S.
Source : Human Plasma
Species : Human
Form : Frozen
Molecular Mass : ~ 570,000 (whole molecule)~ 70-75,000 (alpha chains)~ 40-45,000 (beta chain)
Purity : >= 95% by SDS-PAGE
Usage : For research use only
Quality Control Test : Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Stability : >1 year
Storage : <=>
Storage Buffer : 10 mM Tris, pH 7.4, with 100 mM NaCl+ 0.05% NaN3
Gene Name : C4BPB complement component 4 binding protein, beta [ Homo sapiens ]
Official Symbol : C4BPB
Synonyms : C4BPB; complement component 4 binding protein, beta; C4BP, complement component 4 binding protein, beta; C4b-binding protein beta chain; C4b binding protein; beta chain; complement component 4 binding protein; C4BP;
Gene ID : 725
mRNA Refseq : NM_000716
Protein Refseq : NP_000707
MIM : 120831
UniProt ID : P20851
Chromosome Location : 1q32
Pathway : Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Pertussis, organism-specific biosystem;

Products Types

◆ Recombinant Protein

C4BPB-0054HRecombinant Human C4BPB Protein, GST-Tagged+Inquiry
C4BPB-10533HRecombinant Human C4BPB, His-tagged+Inquiry
C4BPB-26312THRecombinant Human C4BPB+Inquiry
C4BPB-6970HRecombinant Human Complement Component 4 Binding Protein, Beta, His-tagged+Inquiry

See All C4BPB Recombinant Protein

◆ Lysates

C4BPB-8036HCLRecombinant Human C4BPB 293 Cell Lysate+Inquiry

See All C4BPB Lysates

Related Gene

C12orf5C19orf10C1QBC1QBPC1QL2C1QTNF1C1QTNF2C1QTNF5C1QTNF6C1QTNF7C1qtnf9C1sC2C4orf7C5C6orf108C11orf30C13orf1C17orf75C1DC1GALT1C1orf38C1QCC20orf30C21orf33C3C4BC5orf32C6orf115C9orf86C9orf96C8BC18orf1C1QAC17orf28C21orf59C20orf43C10orf82C15orf40C16orf72C1orf50C2orf40C9orf41C1QTNF3C1QTNF8C5AR1C10orf2C13orf15C15orf15C15orf29C20orf7C2orf28C3orf10C4AC4BPAC4BPBC4orf6C6C7orf10C7orf16C7orf38C9C9orf95C20orf20C14orf129C16orf53C10orf81C11orf17C12orf24C13orf31C14orf126C16orf35C17orf37C17orf88C18orf23C19orf50C1orf163C1orf57C1orf67C1orf89C21orf2C2orf62C4orf43C6orf199C9orf103C9orf98CC14ORF169C3AR1C14ORF166C19ORF2C19ORF43C1RC20ORF3C7C8AC8GC8orf44-SGK3C14ORF159C10ORF67C16ORF58C21ORF63C10ORF57C10ORF62C11ORF24C11ORF46C3ORF64C10ORF137C13ORF33C10ORF129C11ORF2C8ORF33C7ORF42C6ORF118C7ORF58C14ORF180C14ORF21C14ORF28C14ORF37C1ORF96C12ORF49C12ORF50C12ORF53C9ORF100C9ORF114C13ORF26C13ORF30C11ORF21C9ORF64C9ORF68C10ORF116C21ORF7C14ORF133C14ORF135C17ORF48C17ORF49C17ORF53C11ORF53C11ORF54C5ORF24C5ORF35C5ORF4C5ORF51C17ORF56C17ORF57C1ORF110C1ORF111C1ORF122C1ORF127C1ORF129C7ORF43C7ORF44C7ORF50C16ORF61C16ORF62C16ORF70C16ORF71C16ORF73C16ORF78C16ORF87C17ORF104C17ORF39C17ORF42C14ORF177C14ORF80C15ORF27C15ORF32C15ORF33C15ORF38C15ORF39C15ORF17C15ORF24C15ORF26C15ORF41C15ORF44C15ORF52C15ORF62C16ORF13C16ORF45C16ORF46C16ORF48C16ORF5C16ORF57C1ORF94C1ORF95C21ORF91C22ORF13C22ORF25C22ORF36C2CD2C2CD4CC2ORF18C9ORF89C9ORF153C9ORF156C20ORF72C20ORF79C10ORF93C10ORF95C11ORF16C9ORF78C3ORF62C3ORF67C3ORF70C3ORF75C6ORF201C6ORF223C6ORF25C21ORF56C3ORF15C3ORF17C3ORF18C6ORF1C6ORF10C2ORF89C10ORF88C1ORF87C1ORF93C14ORF105C11ORF73C11ORF74C11ORF85C11ORF87C1ORF84C1QL1C1QL3C20ORF132C20ORF134C20ORF141C20ORF144C5ORF20C20ORF194C20ORF195C20ORF196C20ORF24C20ORF4C21ORF58C21ORF62C2ORF27AC2ORF29C2ORF3C2ORF42C2ORF43C2ORF47C2ORF50C2ORF53C2ORF55C2ORF56C2ORF57C2ORF68C2ORF69C2ORF80C10ORF140C10ORF46C10ORF47C11ORF57C11ORF63C11ORF65C11ORF67C11ORF71C12ORF11C12ORF29C12ORF4C12ORF40C12ORF42C12ORF48C19ORF55C19ORF56C19ORF73C1GALT1C1C12ORF54C12ORF61C12ORF63C12ORF66C12ORF68C14ORF118C18ORF8C19ORF18C19ORF21C19ORF24C19ORF28C19ORF45C19ORF46C19ORF47C19ORF52C19ORF54C17ORF59C17ORF64C17ORF66C17ORF74C17ORF77C17ORF78C17ORF80C17ORF81C20ORF107C20ORF11C20ORF111C20ORF112C1ORF65C6ORF58C6ORF62C7ORF61C7ORF62C7ORF64C9ORF117C9ORF123C17ORF82C17ORF97C18ORF10C18ORF25C18ORF34C18ORF54C18ORF56C1ORF100C1ORF131C1ORF141C1ORF144C1ORF159C1ORF172C1ORF177C1ORF182C1ORF183C1ORF186C1ORF187C1ORF190C7ORF23C1ORF216C1ORF31C1ORF43C1ORF51C1ORF52C1ORF53C1ORF54C1ORF55C1ORF56C1ORF74C1RLC20ORF160C20ORF165C20ORF173C20ORF177C3ORF23C3ORF24C3ORF33C3ORF37C3ORF38C3ORF39C3ORF58C4ORF19C4ORF22C4ORF27C4ORF32C4ORF33C4ORF36C4ORF44C4ORF45C4ORF46C4ORF47C6ORF64C6ORF70C6ORF81C6ORF97C7ORF29C8ORF34C8ORF45C8ORF48C8ORF59C5ORF54C5ORF55C5ORF60C6ORF120C6ORF127C6ORF146C6ORF174C6ORF192C8ORF76C8ORF84C9ORF174C9ORF25C9ORF3C9ORF30C9ORF4C9ORF40C9ORF43C9ORF46C7ORF31C9ORF128C9ORF150C9ORF152C9ORF167C9ORF170C19ORF29C11ORF68C9ORF9C9ORF82C20ORF54C1QTNF4C6ORF94C10ORF28C14ORF1C19ORF40C5ORF64C2CD4BC2ORF63C17ORF70C10ORF54C19ORF38C22ORF31C19ORF33C19ORF6C5ORF41C20ORF201C20ORF203C5ORF39C10ORF96C7ORF49C1ORF35C4ORF49C14ORF49C1ORF63C12ORF75C5ORF13C9ORF102C10ORF27C22ORF42C13ORF27C11ORF58C1ORF116C2ORF51C2CD2LC7ORF11C3ORF52C11H16ORF80C1rbC. albicansC15orf55C8orf86C1orf229C20orf78C17orf105C17orf108C9orf172C1orf228C10orf107C14orf2C14orf166BC19orf44C19orf57C19orf59C19orf60C19orf66C19orf70C20orf26C10orf111C10orf113C10orf118C10orf12C10orf120C10orf128C10orf32C10orf35C10orf53C10orf55C10orf68C10orf71C10orf90C10orf91C11orf1C11orf10C11orf34C11orf45C11orf48C11orf49C11orf52C11orf70C11orf80C11orf84C11orf86C11orf9C12orf23C12orf39C12orf43C12orf45C12orf52C12orf60C12orf70C12orf71C12orf73C14orf101C14orf43C14orf45C14orf93C15orf23C15orf43C15orf53C15orf57C15orf59C16orf79C16orf80C16orf88C17orf47C17orf58C17orf67C17orf99C18orf26C18orf32C18orf62C19orf26C19orf42C1orf105C1orf106C1orf109C1orf112C1orf114C1orf123C1orf158C1orf162C1orf168C1orf173C1orf174C1orf192C1orf194C1orf198C1orf21C1orf27C1orf61C1orf64C1orf68C1orf85C1orf86C20orf151C20orf152C20orf166C22orf15C22orf23C22orf28C22orf29C22orf32C2CD3C2orf44C2orf65C2orf66C2orf72C2orf76C2orf83C3orf20C3orf26C4orf21C4orf3C4orf40C5orf15C5orf22C5orf34C5orf44C5orf48C6orf106C6orf130C6orf132C6orf15C6orf162C6orf163C6orf165C6orf195C6orf222C6orf225C6orf57C6orf89C8orf58C8orf74C9orf11C9orf116C9orf131C9orf135C9orf139C7orf25C7orf34C7orf41C7orf45C7orf53C7orf57C7orf59C7orf60C8orf40C8orf4C8orf42C8orf44C8orf47C9orf16C9orf163C9orf169C9orf37C9orf57C9orf50C9orf66C9orf84C9orf91C19ORF76C8orf85C15ORF38-AP3S2C1orf115C1ORF233C10orf11C11orf20C11orf35C11orf40C11orf83C11orf88C11ORF93C11ORF94C11ORF95C13orf35C14orf178C16orf55C17orf100C17orf102C17ORF107C17orf79C17orf96C19orf69C2orf27BC2orf48C2orf88C2ORF91C22orf24C22orf26C4orf17C5ORF63C6ORF228C6orf47C6orf52C7orf26C8orf37C8orf82C8ORF87C1QL4C19orf63C87977C030019I05RikC530028O21RikC330019G07RikC5ORF65C030006K11RikC030030A07RikC030039L03RikC030046E11RikC030046I01RikC030048B08RikC330005M16RikC330006K01RikC330007P06RikC330018D20RikC330021F23RikC330027C09RikC530008M17RikC630004H02RikC5ORF62C17ORF109C17ORF110C15orf42C3orf71C1QTNF9BC2cd4aC2cd4dC1orf101C1orf146C1orf185C1orf189C1orf204C1orf210C1orf212C1orf226C1orf227C1H6orf35C10orf105C10orf131C10orf76C11orf31C11orf91C11orf96C12orf44C12orf56C12orf57C12orf76C14orf142C14orf182C14orf79C15orf56C15orf60C15orf61C16orf3C16orf52C16orf59C16orf82C16orf86C16orf89C16orf90C16orf91C16orf92C16orf93C16orf95C17orf72C17orf89C18orf42C18orf63C19orf48C19orf71C19orf77C2orf15C2orf49C2orf54C2orf61C2orf70C2orf73C2orf74C2orf78C2orf81C2orf82C20orf118C20orf85C22orf46C3orf14C3orf22C3orf35C3orf43C3orf45C3orf79C3orf80C4orf29C4orf34C4orf48C4orf51C4orf52C5orf30C5orf38C5orf42C5orf45C5orf47C5orf52C5orf58C6orf136C6orf141C6orf170C6orf203C6orf211C6orf226C6orf48C6orf99C7orf33C7orf63C7orf65C7orf66C7orf71C7orf73C8orf46C8orf73C9orf129C9orf142C9orf171C9orf24C9orf47C9orf85C130022K22RikC3orf19C14orf38C1raC4bpC77080C77370C78339C80913C86695C87414C87436C130026I21RikC130039O16RikC130050O18RikC130060K24RikC130074G19RikC130079G13RikC230052I12RikC230081A13RikC20orf94C3orf78C3orf77C14orf176C16orf7C2orf39C11orf42C12orf65C15orf48C19orf80C11H2orf49

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