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Recombinant Chicken ALDOB

Cat.No. : ALDOB-1817C
Product Overview : Recombinant Chicken ALDOB full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Chicken
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : ALDOB aldolase B, fructose-bisphosphate [ Gallus gallus (chicken) ]
Official Symbol : ALDOB
Gene ID : 427308
Protein Refseq : NP_001007978
UniProt ID : P07341

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How is the ALDOB protein related to hereditary fructose intolerance (HFI)? 10/27/2022

Hereditary fructose intolerance is caused by a genetic mutation in the ALDOB gene, which leads to a deficiency or complete absence of the ALDOB protein. Without functioning ALDOB protein, the body is unable to properly metabolize fructose, leading to a build-up of toxic byproducts and causing the symptoms of HFI.

Are there different types of mutations in the ALDOB gene associated with hereditary fructose intolerance? 09/02/2020

Yes, there are multiple mutations identified in the ALDOB gene that can cause hereditary fructose intolerance. These mutations can vary in their severity and impact on the function of the ALDOB protein.

Can mutations in the ALDOB gene have other health implications besides hereditary fructose intolerance? 12/28/2019

Yes, mutations in the ALDOB gene can have other health implications. In some cases, mutations that cause a partial deficiency of the ALDOB protein may lead to a milder form of fructose intolerance or cause symptoms only when excessive amounts of fructose are consumed. Additionally, there is some evidence to suggest that ALDOB gene mutations may be associated with an increased risk of developing certain types of liver diseases. However, further research is needed to fully understand the potential implications.

Can hereditary fructose intolerance be detected before birth? 10/13/2019

Yes, prenatal testing is available for hereditary fructose intolerance. It involves analyzing fetal DNA obtained through procedures like chorionic villus sampling (CVS) or amniocentesis to identify mutations in the ALDOB gene. This allows for early detection of the condition, aiding in family planning and preparation for managing the condition after birth.

Are there any other functions or roles of the ALDOB protein besides fructose metabolism? 06/28/2019

The ALDOB protein is primarily involved in fructose metabolism, but it also has other functions. It plays a role in gluconeogenesis, a process in which the liver produces glucose from non-carbohydrate sources. It is also involved in maintaining the balance of sugar molecules in the body and supporting normal liver function.

How is hereditary fructose intolerance diagnosed? 09/19/2016

Hereditary fructose intolerance is typically diagnosed through a combination of clinical symptoms, biochemical testing, and genetic testing. Symptoms of the condition may include abdominal pain, nausea, vomiting, and low blood sugar levels. Biochemical testing involves measuring the levels of certain metabolites, such as fructose and its byproducts, in the blood or urine. Genetic testing can confirm the presence of specific mutations in the ALDOB gene.

Customer Reviews (3)

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Reviews
03/02/2021

    It has been extensively used in protein-protein interaction studies, enzymatic assays, and structural analyses, showcasing its reliability and adaptability in diverse research areas.

    01/18/2021

      With the ALDOB Protein, I have the confidence to generate critical insights and drive significant advancements in my field.

      02/16/2020

        I am certain of obtaining reliable and reproducible results, enabling me to contribute to scientific progress and make new discoveries.

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