|Cat. No. :
|Product Overview :
||Recombinant mouse IL-1β, fused to His tag, was expressed in E.coli and purified by using conventional chromatography techniques,21kDa (189aa).
||IL-1β is an inflammatory cytokine that might modulate angiogenesis by directly interacting with vascular endothelial cells or enhancing the production of proangiogenic factors via paracrine control. IL-1β stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL-1β is required for tumor growth, metastasis, and angiogenesis in several animal models.
|Sequences of amino acids :
||MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMVPI RQLHYRLRDE QQKSLVLSDP YELKALHLNG QNINQQVIFS MSFVQGEPSN DKIPVALGLK GKNLYLSCVM KDGTPTLQLE SVDPKQYPKK KMEKRFVFNK IEVKSKVEFE SAEFPNWYIS TSQAEHKPVF LGNNSGQDII DFTMESVSS
||Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
||> 90% by SDS - PAGE
||1 mg/ml (determined by Bradford assay)
||Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
|PDBrendering based on 31bi. Available structures:1hib,1i1b,1iob,1itb,1l2h,1s0l,1t4q,1too,1tp0,1twe,1twm,21bi,2i1b,2nvh,31bi,41bi,4i1b,5i1b,6i1b,7i1b,9ilb :