Recombinant Glycosylated Rat PAI-1 Stable Mutant

• Cat.No.: Serpine1 -98R
• Product Overview: Glycosylated rat PAI-1 produced in insect cells with a single conservative mutation (Isoleucine 91 to Leucine) to increase stability.

Specification

• Source: Insect cell
• Species: Rat
• Form: Frozen liquid
• Molecular Mass: 46,000
• Purity: >95% by SDS-PAGE analysis
• Characteristic: 90% active by uPA titration and SDS-PAGE
• Usage: For in vitro laboratory use only
• Notes: Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet.
• Storage: -70°C
• Concentration: 1.0 mg/ml
• Storage Buffer: 0.05M Sodium Acetate; 0.1M NaCl; 1mM EDTA; pH 5.0
• Shipping: Dry ice

Gene Information

• Gene Name: Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 [ Rattus norvegicus ]
• Official Symbol: Serpine1
• Synonyms: SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; plasminogen activator inhibitor 1; PAI; PAI-1; serpin E1; endothelial plasminogen activator inhibitor; serine (or cysteine) proteinase inhibitor, member 1; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Pai1; PAI1A; Planh; Pai1aa; RATPAI1A
• Gene ID: 24617
• mRNA Refseq: NM_012620
• Protein Refseq: NP_036752
• UniProt ID: P20961
• Chromosome Location: 12q11-q12
• Pathway: Adipogenesis, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem
• Function: peptidase inhibitor activity; protease binding; protease binding; receptor binding; contributes_to receptor binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity