Recombinant Mouse MMP-2/TIMP-2 Complex
Cat.No. : | Mmp2-44M |
Product Overview : | Matrix Metalloproteinase 2 - TIMP-2 Complex (MMP-2, Gelatinase A, 72 kDa Type IV Collagenase, EC 3.4.24.24) from mouse fibroblasts. |
- Specification
- Gene Information
- Related Products
Source : | Mouse fibroblasts |
Species : | Mouse |
Form : | Liquid, in 50 mM Tris/HCl, pH 7.0, 200 mM NaCl, 5 mM CaCl2, 1 μM ZnCl2, 0.05% NaN3, 0.05% Brij 35 |
Purity : | >95%, homogenous by electrophoresis and Western Blotting analysis |
Storage : | if stored at -70°C. The enzyme can be kept at -20°C for several weeks without significant loss of activity. Repeated freezing and thawing must be avoided. Do always keep the enzyme on ice. If kept at room temperature for hours without substrate the enzyme looses significant activity! |
Gene Name : | Mmp2 matrix metallopeptidase 2 [ Mus musculus ] |
Official Symbol : | Mmp2 |
Synonyms : | MMP2; matrix metallopeptidase 2; 72 kDa type IV collagenase; gelatinase A; 72kD gelatinase; 72kDa gelatinase; 72 kDa gelatinase; 72kD type IV collagenase; 72kDa type IV collagenase; matrix metalloproteinase 2; matrix metalloproteinase-2; GelA; Clg4a; MMP-2; |
Gene ID : | 17390 |
mRNA Refseq : | NM_008610 |
Protein Refseq : | NP_032636 |
Pathway : | Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; GnRH signaling pathway, organism-specific biosystem; GnRH signaling pathway, conserved biosystem; IL-3 Signaling Pathway, organism-specific biosystem; |
Function : | fibronectin binding; hydrolase activity; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
Mmp2-1784M | Recombinant Mouse Mmp2 Protein, His-tagged | +Inquiry |
MMP2-1121H | Recombinant Human MMP2 Protein, His-tagged | +Inquiry |
MMP2-3371R | Recombinant Rat MMP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mmp2-1783M | Recombinant Mouse Mmp2 Protein, His-tagged | +Inquiry |
MMP2-562H | Recombinant Human MMP2 Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
MMP2-8455M | Native Mouse MMP2 | +Inquiry |
MMP2-47H | Native Human MMP-2/TIMP-2 Complex | +Inquiry |
MMP2-46H | Native Human MMP-2 | +Inquiry |
◆ Lysates | ||
MMP2-2380HCL | Recombinant Human MMP2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0320C | MMP2 Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe activity of MMP2 is regulated by inhibitors and antibodies against it to inhibit tumor metastasis and invasion.
MMP2 interacts with some transfer factors, such as VEGF and EGF, to promote tumor metastasis and invasion.
Inhibitors of MMP2 can be used as potential drug targets for the treatment of tumors, cardiovascular diseases and other related diseases.
MMP2 interacts with tumor cells, immune cells, blood vessels, etc. in the tumor microenvironment to affect tumor progression and treatment effect.
It is involved in important processes such as morphogenesis, organ development and intraembryonic lymphatic vessel formation during embryonic development.
Mutations in MMP2 may affect its protein structure and function, leading to the occurrence and progression of related diseases.
Customer Reviews (3)
Write a reviewThe solubility and ion exchange ability are very good, which is convenient for subsequent experimental treatment and purification.
Kinetic parameters such as enzymatic reaction rate and binding affinity were tested in the early stage, and it was found that the protein performed well.
MMP2 products undergo strict quality control to ensure the consistency and stability of each batch.
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