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Recombinant Human UBE2Q2, His-tagged

Cat.No. : UBE2Q2-101H
Product Overview : Recombinant human UBE2Q2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : UBE2Q2 also known as Ubiquitin-conjugating enzyme E2 Q2 isoform1. UBE2Q2 Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes Lys-48-linked polyubiquitination. This protein detected in hypopharyngeal head and neck squamous cell carcinoma, in tumor masses and invasive epithelium. It belongs to the ubiquitin-conjugating enzyme family.
Source : E.coli
Species : Human
Tag : His
Form : Liquid. In Phosphate Buffer Saline (pH7.4) containing 30% glycerol, 1mM DTT
Molecular Mass : 45.2kDa (398aa) confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMSVSGLK AELKFLASIF DKNHERFRIV SWKLDELHCQ FLVPQQGSPH SLPPPLTLHC NITESYPSSS PIWFVDSEDP NLTSVLERLE DTKNNNLLRQ QLKWLICELC SLYNLPKHLD VEMLDQPLPT GQNGTTEEVT SEEEEEEEEM AEDIEDLDHY EMKEEEPISG KKSEDEGIEK ENLAILEKIR KTQRQDHLNG AVSGSVQASD RLMKELRDIY RSQSYKTGIY SVELINDSLY DWHVKLQKVD PDSPLHSDLQ ILKEKEGIEY ILLNFSFKDN FPFDPPFVRV VLPVLSGGYV LGGGALCMEL LTKQGWSSAY SIESVIMQIN ATLVKGKARV QFGANKNQYN LARAQQSYNS IVQIHEKNGW YTPPKEDG
Purity : >85% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5mg/ml (determined by Absorbance at 280nm)
Gene Name : UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 [ Homo sapiens ]
Official Symbol : UBE2Q2
Synonyms : UBE2Q2; ubiquitin-conjugating enzyme E2Q family member 2; ubiquitin conjugating enzyme E2Q (putative) 2; ubiquitin-conjugating enzyme E2 Q2; DKFZp762C143; ubiquitin-protein ligase Q2; ubiquitin carrier protein Q2;
Gene ID : 92912
mRNA Refseq : NM_001145335
Protein Refseq : NP_001138807
MIM : 612501
UniProt ID : Q8WVN8
Chromosome Location : 15q24.2
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem;
Function : ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; ubiquitin-protein ligase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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