Recombinant Rat Csf1 Csf1-13R

Recombinant Rat Csf1


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Recombinant Rat Csf1

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Cat.No. : Csf1-13R
Product Overview : MCSF Rat Recombinant produced in HEK-293 cells is a secreted protein (amino acids Glu33-Arg254). M-CSF is disulfide-linked homodimer containing 2 x 222 a.a chains.
Description : Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.
Source : HEK293
Species : Rat
Form : Sterile Filtered White lyophilized (freeze-dried) powder. The recombinant MCSF was lyophilized after extensive dialysis against PBS.
Bio-activity : The ED50 of 3-4ng/ml is measured by its ability to stimulate the proliferation of mouse M-NFS-60 cells.
Purity : Greater than 95.0% as determined by SDS-PAGE.
Stability : Lyophilized MCSF although stable at room temperature for 3 weeks, should be stored desiccated below -18ºC. Upon reconstitution MCSF should be stored at 4ºC between 2-7 days and for future use below -18ºC. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Reconstitution : It is recommended to reconstitute the MCSF in sterile PBS not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Gene Name : Csf1 colony stimulating factor 1 (macrophage) [ Rattus norvegicus (Norway rat) ]
Official Symbol : Csf1
Synonyms : Csf1; colony stimulating factor 1 (macrophage); macrophage colony-stimulating factor 1; CSF-1; MCSF; NP_076471.3; EC
Gene ID : 78965
mRNA Refseq : NM_023981
Protein Refseq : NP_076471
UniProt ID : Q8JZQ0
Chromosome Location : 2q34
Pathway : Cytokine-cytokine receptor interaction; Cytokines and Inflammatory Response (BioCarta); Hematopoietic cell lineage
Function : cytokine activity; growth factor activity; macrophage colony-stimulating factor receptor binding

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