Recombinant Human PAWR, MYC/DDK-tagged PAWR-19H

Recombinant Human PAWR, MYC/DDK-tagged


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Recombinant Human PAWR, MYC/DDK-tagged

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Cat.No. : PAWR-19H
Product Overview : Recombinant Human PAWR, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description : The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
Source : HEK293 cells
Species : Human
Molecular Mass : 36.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : PAWR PRKC, apoptosis, WT1, regulator [ Homo sapiens (human) ]
Official Symbol : PAWR
Synonyms : PAWR; PRKC, apoptosis, WT1, regulator; PAR4; Par-4; PRKC apoptosis WT1 regulator protein; WT1-interacting protein; prostate apoptosis response 4 protein; prostate apoptosis response protein 4; prostate apoptosis response protein PAR-4; prostate apoptosis response-4; transcriptional repressor PAR4
Gene ID : 5074
mRNA Refseq : NM_002583
Protein Refseq : NP_002574
MIM : 601936
UniProt ID : Q96IZ0
Chromosome Location : 12q21
Pathway : Ceramide signaling pathway; Coregulation of Androgen receptor activity; IL-4 signaling Pathway
Function : actin binding; enzyme binding; leucine zipper domain binding; rotein binding

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