"PAWR" Related Products

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Recombinant Human PAWR, MYC/DDK-tagged

Cat.No.: PAWR-19H
Product Overview: Recombinant Human PAWR, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description: The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
Source: HEK293 cells
Species: Human
Tag: MYC/DDK
Molecular Mass: 36.4 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name: PAWR PRKC, apoptosis, WT1, regulator [ Homo sapiens (human) ]
Official Symbol: PAWR
Synonyms: PAWR; PRKC, apoptosis, WT1, regulator; PAR4; Par-4; PRKC apoptosis WT1 regulator protein; WT1-interacting protein; prostate apoptosis response 4 protein; prostate apoptosis response protein 4; prostate apoptosis response protein PAR-4; prostate apoptosis response-4; transcriptional repressor PAR4
Gene ID: 5074
mRNA Refseq: NM_002583
Protein Refseq: NP_002574
MIM: 601936
UniProt ID: Q96IZ0
Chromosome Location: 12q21
Pathway: Ceramide signaling pathway; Coregulation of Androgen receptor activity; IL-4 signaling Pathway
Function: actin binding; enzyme binding; leucine zipper domain binding; rotein binding

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