Recombinant Human PAWR, MYC/DDK-tagged

• Cat.No.: PAWR-19H
• Product Overview: Recombinant Human PAWR, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Description: The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
• Source: HEK293 cells
• Species: Human
• Tag: MYC/DDK
• Molecular Mass: 36.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: PAWR PRKC, apoptosis, WT1, regulator [ Homo sapiens (human) ]
• Official Symbol: PAWR
• Synonyms: PAWR; PRKC, apoptosis, WT1, regulator; PAR4; Par-4; PRKC apoptosis WT1 regulator protein; WT1-interacting protein; prostate apoptosis response 4 protein; prostate apoptosis response protein 4; prostate apoptosis response protein PAR-4; prostate apoptosis response-4; transcriptional repressor PAR4
• Gene ID: 5074
• mRNA Refseq: NM_002583
• Protein Refseq: NP_002574
• MIM: 601936
• UniProt ID: Q96IZ0
• Chromosome Location: 12q21
• Pathway: Ceramide signaling pathway; Coregulation of Androgen receptor activity; IL-4 signaling Pathway
• Function: actin binding; enzyme binding; leucine zipper domain binding; rotein binding