Recombinant Human B2M, His-tagged

Cat.No.: B2M-1656H
Product Overview: Recombinant Human B2M(Ile 21 - Met 119), fused with 6×His tag at the C-terminus, was expressed in human 293 cells.
Description: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Source: HEK293
Species: Human
Tag: His
Predicted N Terminal: Ile 21
Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass: rhB2M, fused with 6×His tag at the C-terminus, has a calculated MW of 12.6 kDa. The predicted N-terminus is Ile 21. DTT-reduced Protein migrates as 13 kDa.
Endotoxin: Less than 1.0 EU per μg of the rhB2M by the LAL method.
Purity: >98% as determined by SDS-PAGE.
Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4ºC-8ºC); After reconstitution under sterile conditions for 1 month (4ºC-8ºC) or 3 months (-20ºC to -70ºC).
Reconstitution: See Certificate of Analysis for details of reconstitution instruction and specific concentration.
Gene Name: B2M beta-2-microglobulin [ Homo sapiens (human) ]
Official Symbol: B2M
Synonyms: B2M; beta-2-microglobulin; Beta-2 microglob ulin form pI 5.3; beta-2-microglobin; beta chain of MHC class I molecules
Gene ID: 567
mRNA Refseq: NM_004048
Protein Refseq: NP_004039
MIM: 109700
UniProt ID: P61769
Chromosome Location: 15q21.1
Pathway: Antigen processing and presentation; HIV Infection; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Function: protein binding; identical protein binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.