Recombinant Dog Interleukin-18
Cat.No. : | IL18-01D |
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- Gene Information
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Source : | E. coli |
Species : | Dog |
Form : | 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, 5% Trehalose, pH7.4. |
Molecular Mass : | ~18kDa |
AA Sequence : | YFGKLEPKLSIIRNLNDQVLFVNEG NQPVFEDMPDSDCTDNAPHTIFIIY MYKDSLTRGLAVTISVKYKTMSTLS CKNKTISFQKMSPPDSINDEGNDII FFQRSVPGHDDKIQFESSLYKGHFL ACKKENDLFKLILKDKDENGDKSIM FTVQNKS |
Purity : | >95% as determined by SDS-PAGE |
Storage : | Short Term Storage +4°C, Long Term Storage -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
Reconstitution : | It is recommended to reconstitute the lyophilized Dog IL18 in sterile and pre-cooled ddH2O not less than 0.1mg/ml, which can then be further diluted to other aqueous solutions. |
Gene Name : | IL18 interleukin 18 (interferon-gamma-inducing factor) [ Canis lupus familiaris ] |
Official Symbol : | il18 |
Synonyms : | IL18; interleukin 18 (interferon-gamma-inducing factor); interleukin-18; IL-18; IL-1 gamma; interleukin-1 gamma; IFN-gamma-inducing factor; interferon gamma inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; IGIF; |
Gene ID : | 403796 |
mRNA Refseq : | NM_001003169 |
Protein Refseq : | NP_001003169 |
Pathway : | African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Influenza A, organism-specific biosystem; |
Products Types
◆ Recombinant Protein | ||
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Il18-1013M | Recombinant Mouse Il18 Protein, His-tagged | +Inquiry |
IL18-1010G | Recombinant Goat IL18 Protein, His-tagged | +Inquiry |
IL18-154H | Recombinant Active Human IL18 Protein, His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
IL18-344HCL | Recombinant Human IL18 lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionCo-immunoprecipitation, co-localization studies, and pathway inhibition assays decipher IL18's interactions with signaling molecules and pathways.
Therapeutic antibody trials, in vitro drug screens, and disease model assessments assess IL18-targeted interventions in autoimmune diseases.
Xenograft models, intravital imaging, and tissue-specific knockout approaches unravel IL18's kinetics and effects within complex in vivo environments.
Flow cytometry, chemotaxis assays, and functional cell assays examine IL18's impact on immune cell activation, migration, and effector functions.
Surface plasmon resonance, mutational studies, and phosphoproteomics illuminate IL18's receptor interactions and downstream signal transduction pathways.
Immunophenotyping, cytokine profiling, and gene expression analyses elucidate IL18's influence on Th cell polarization and immune balance.
ChIP assays, promoter analyses, and epigenetic profiling uncover the regulatory mechanisms underlying IL18 gene expression dynamics.
Disease models, knockout mice, and co-stimulation studies explore IL18's involvement in inflammatory conditions and its interplay with other proinflammatory mediators.
Tumor models, immune profiling, and immunotherapeutic studies investigate IL18's modulation of the tumor microenvironment and its implications for cancer therapy.
Caspase assays, cytokine ELISAs, and microscopy techniques unveil the activation of inflammasomes and IL18's contribution to pyroptosis and cytokine storms.
Customer Reviews (3)
Write a reviewEffective in inflammation models.
High stability in serum.
Suitable for ELISA.
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