Recombinant Human IL1R1/IL1RAcP, Fc-tagged therapeutic protein
Cat.No. : | IL1R1&IL1RAcP-P01H |
Product Overview : | Recombinant Human IL-1R1&IL-1RAcP, Fc-tagged therapeutic protein, also known as IL-1 Trap, is an interleukin 1 inhibitor.The protein is a dimeric fusion protein consisting of the ligand-binding domains of the extracellular portions of the human interleukin-1 receptor component (IL-1R1) and IL-1 receptor accessory protein (IL-1RAcP) linked in-line to the fragment-crystallizable portion (Fc region) of human IgG1 that binds and neutralizes IL-1. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. |
Species : | Human |
Tag : | Fc |
Endotoxin : | < 0.1 EU per μg of the protein |
Purity : | >95% |
Gene Name : | IL1R1 interleukin 1 receptor, type I [ Homo sapiens ] |
Official Symbol : | IL1R1 |
Synonyms : | IL1R1; interleukin 1 receptor, type I; IL1R, IL1RA; interleukin-1 receptor type 1; CD121A; D2S1473; IL-1R-1; IL-1RT1; IL-1RT-1; antigen CD121a; interleukin receptor 1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family member A; interleukin 1 receptor alpha, type I; P80; IL1R; IL1RA; IL-1R-alpha; |
Gene ID : | 3554 |
mRNA Refseq : | NM_000877 |
Protein Refseq : | NP_000868 |
MIM : | 147810 |
UniProt ID : | P14778 |
Chromosome Location : | 2q12 |
Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | interleukin-1 receptor activity; interleukin-1, Type I, activating receptor activity; platelet-derived growth factor receptor binding; protease binding; protein binding; receptor activity; signal transducer activity; transmembrane signaling receptor activity; |
Products Types
◆ Recombinant Protein | ||
IL1R1-3147H | Recombinant Human IL1R1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL1R1-02H | Active Recombinant Human IL1R1 Protein (19-328aa), C-His-tagged | +Inquiry |
IL1R1-164H | Recombinant Human IL1R1 Protein (ECD), His-tagged(C-ter) | +Inquiry |
Il1r1-10581M | Recombinant Mouse Il1r1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL1R1-064H | Recombinant Human IL1R1 Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
IL1R1-945CCL | Recombinant Cynomolgus IL1R1 cell lysate | +Inquiry |
IL1R1-1120HCL | Recombinant Human IL1R1 cell lysate | +Inquiry |
IL1R1-1787MCL | Recombinant Mouse IL1R1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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