Active Recombinant Human ITGA6

• Cat.No.: ITGA6-609H
• Product Overview: Recombinant Human ITGA6 (Accession # NP_000201 (Integrin alpha 6) & P16144 (Integrin beta 4)) was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Source: CHO cells
• Species: Human
• Predicted N Terminal: Phe24 ( alpha 6) & Asn28 ( beta 4)
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When Mouse Laminin I is coated at 10 µg/mL, Recombinant Human Integrin alpha 6 beta 4 binds with an apparent KD <5 nM.
• Molecular Mass: Recombinant Human ITGA6 has a calculated MW of 104 kDa ( alpha 6) & 84.8 kDa ( beta 4). In SDS-PAGE migrates as 125-135 kDa ( alpha 6) & 100-110 kDa ( beta 4), reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme [ Homo sapiens ]
• Official Symbol: PPP3CA
• Synonyms: PPP3CA; protein phosphatase 3, catalytic subunit, alpha isozyme; CALN, CALNA, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha); serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; calcineurin A alpha; CNA1; PPP2B; protein phosphatase 2B; catalytic subunit; alpha isoform; CAM-PRP catalytic subunit; calmodulin-dependent calcineurin A subunit alpha isoform; protein phosphatase 2B, catalytic subunit, alpha isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; CALN; CCN1; CALNA; CALNA1
• Gene ID: 5530
• mRNA Refseq: NM_000944
• Protein Refseq: NP_000935
• MIM: 114105
• UniProt ID: Q08209
• Chromosome Location: 4q24