Recombinant Human TGFBR2, Fc Chimera TGFBR2-646H

Cat.No.:	TGFBR2-646H
Product Overview:	Recombinant Human TGFBR2 (Accession # NP_001020018) was produced in Mouse myeloma cell line, NS0-derived.
Source:	NSO cells
Species:	Human
Tag:	Fc Chimera
Predicted N Terminal:	Thr23 & Ile24
Form:	Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity:	Measured by its ability to inhibit TGF-beta 1 activity on HT-2 mouse T cells. Tsang, M. et al. (1995) Cytokine 7:389.The ED50 for this effect is typically 1-3 ng/mL in the presence of 0.1 ng/mL of recombinant human TGF-beta 1.
Molecular Mass:	Recombinant Human TGFBR2, Fc Chimera has a calculated MW of 45 kDa (monomer). In SDS-PAGE migrates as 65-75 kDa, reducing conditions.
Purity:	>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage:	Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

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Gene Name:	TGFBR2 transforming growth factor, beta receptor II (70/80kDa) [ Homo sapiens ]
Official Symbol:	TGFBR2
Synonyms:	TGFBR2; transforming growth factor, beta receptor II (70/80kDa); MFS2, transforming growth factor, beta receptor II (70 80kD); TGF-beta receptor type-2; tbetaR-II; TGF-beta receptor type II; TGF-beta type II receptor; TGF-beta receptor type IIB; transforming growth factor-beta receptor type II; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; AAT3; FAA3; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII;
Gene ID:	7048
mRNA Refseq:	NM_001024847
Protein Refseq:	NP_001020018
MIM:	190182
UniProt ID:	P37173
Chromosome Location:	3p22

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Research Area

Products > Immunology Proteins > Inflammation / Inflammatory Mediator Proteins > Inflammatory Cytokines & Chemokines and Receptors Proteins > IL-12 Family Proteins

IL-12 Family Proteins

CD4 CD28 STAT3 IL18R1 TGFBR2 JAK2 CCR5 IL23A NFKB1 CXCR3

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