Recombinant Human TGFBR2, Fc Chimera TGFBR2-646H

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Recombinant Human TGFBR2, Fc Chimera

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Cat.No. :	TGFBR2-646H
Product Overview :	Recombinant Human TGFBR2 (Accession # NP_001020018) was produced in Mouse myeloma cell line, NS0-derived.
Source :	NSO cells
Species :	Human
Tag :	Fc Chimera
Predicted N Terminal :	Thr23 & Ile24
Form :	Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity :	Measured by its ability to inhibit TGF-beta 1 activity on HT-2 mouse T cells. Tsang, M. et al. (1995) Cytokine 7:389.The ED50 for this effect is typically 1-3 ng/mL in the presence of 0.1 ng/mL of recombinant human TGF-beta 1.
Molecular Mass :	Recombinant Human TGFBR2, Fc Chimera has a calculated MW of 45 kDa (monomer). In SDS-PAGE migrates as 65-75 kDa, reducing conditions.
Purity :	>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage :	Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Name :	TGFBR2 transforming growth factor, beta receptor II (70/80kDa) [ Homo sapiens ]
Official Symbol :	TGFBR2
Synonyms :	TGFBR2; transforming growth factor, beta receptor II (70/80kDa); MFS2, transforming growth factor, beta receptor II (70 80kD); TGF-beta receptor type-2; tbetaR-II; TGF-beta receptor type II; TGF-beta type II receptor; TGF-beta receptor type IIB; transforming growth factor-beta receptor type II; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; AAT3; FAA3; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII;
Gene ID :	7048
mRNA Refseq :	NM_001024847
Protein Refseq :	NP_001020018
MIM :	190182
UniProt ID :	P37173
Chromosome Location :	3p22