Recombinant Human CD274 protein, His-tagged

Cat.No.: CD274-2145H
Product Overview: Recombinant Human CD274(Phe 19 - Arg 238) fused with His tag at C-terminal was expressed in HEK293.
Source: HEK293
Species: Human
Tag: His
Predicted N Terminal: Phe 19
Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass: Has a calculated MW of 26 kDa. The reducing (R) protein migrates as 35-42 kDa in SDS-PAGE due to glycosylation.
Protein length: Phe 19 - Arg 238
Endotoxin: Less than 1.0 EU per μg of the Human PD-L1, His Tag (HPLC-verified) by the LAL method.
Purity: >98% as determined by SDS-PAGE.>95% as determined by SEC-HPLC.
Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade).
Gene Name: CD274 CD274 molecule [ Homo sapiens ]
Official Symbol: CD274
Synonyms: CD274; CD274 molecule; CD274 antigen , PDCD1LG1, programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; B7 H; B7 H1; B7H1; PD L1; PDL1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; B7-H; PD-L1; PDCD1L1; PDCD1LG1; MGC142294; MGC142296;
Gene ID: 29126
mRNA Refseq: NM_014143
Protein Refseq: NP_054862
MIM: 605402
UniProt ID: Q9NZQ7
Chromosome Location: 9p24.1
Pathway: Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem;
Function: protein binding; protein tyrosine phosphatase activity; receptor activity;

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