Recombinant Human VEGFB, Fc-tagged


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Recombinant Human VEGFB, Fc-tagged

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Cat.No. : VEGFB-275H
Product Overview : Recombinant Human VEGFB(Pro22-Ala207) fussed with Fc region of human IgG1 at N-terminal was expressed in Human Cells.
Description : This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Source : Human Cells
Species : Human
Tag : Fc
Predicted N Terminal : Glu
Form : Lyophilized from sterile PBS, pH 7.4.
Molecular Mass : The recombinant human VEGFB consists 446 amino acids and predicts a molecular mass of 47.8 kDa.
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > (75.2+22) % as determined by SDS-PAGE.
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : VEGFB vascular endothelial growth factor B [ Homo sapiens ]
Official Symbol : VEGFB
Synonyms : VRF; VEGFL; vascular endothelial growth factor B; VEGF-related factor
Gene ID : 7423
mRNA Refseq : NM_003377
Protein Refseq : NP_003368
MIM : 601398
UniProt ID : P49765
Chromosome Location : 11q13
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Heart Development, organism-specific biosystem
Function : chemoattractant activity; growth factor activity; heparin binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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