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Active Recombinant Mouse Thbs1

Cat.No. : Thbs1-659M
Product Overview : Recombinant Mouse Thbs1 (Accession # NP_035710), fused with , was produced in Mouse myeloma cell line, NS0-derived.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian cells
Species : Mouse
Predicted N Terminal : Starts at Asn19
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of SVEC4-10 mouse vascular endothelial cells.The ED50 for this effect is typically 0.1-0.5 µg/mL.
Molecular Mass : Recombinant Mouse Thbs1 has a calculated MW of 129 kDa. In SDS-PAGE migrates as 130-155 kDa, reducing conditions.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : Thbs1 thrombospondin 1 [ Mus musculus ]
Official Symbol : Thbs1
Synonyms : THBS1; thrombospondin 1; thrombospondin-1; TSP1; TSP-1; tbsp1; Thbs-1;
Gene ID : 21825
mRNA Refseq : NM_011580
Protein Refseq : NP_035710
MIM :

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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In which tissues or cell types is THBS1 predominantly expressed? 09/01/2022

THBS1 is widely expressed but is upregulated in response to injury or in certain disease states.

How is THBS1 implicated in cancer progression? 07/10/2021

It can either promote or inhibit cancer progression, depending on the context.

How does THBS1 contribute to cell-matrix interactions? 04/28/2021

It binds to extracellular matrix components, influencing cell attachment and signaling.

What role does THBS1 play in angiogenesis? 09/14/2020

THBS1 acts as an angiogenesis inhibitor, hindering new blood vessel formation.

What therapeutic strategies are being explored targeting THBS1? 03/08/2020

Therapeutic strategies include targeting THBS1 to modulate its effects in cancer and wound healing.

What is the primary function of THBS1 in cellular processes? 06/17/2018

THBS1 modulates cell adhesion, proliferation, and migration.

Are there known genetic variations in THBS1 associated with specific diseases? 02/13/2018

Genetic variations in THBS1 have been linked to cardiovascular diseases and cancer risk.

Customer Reviews (3)

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Reviews
05/14/2022

    Quality exceeded my expectations.

    09/08/2021

      Satisfied customer, will return.

      11/21/2020

        Very pure, excellent results.

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