Active Recombinant Human TREM2 Protein, Fc Chimera

• Cat.No.: TREM2-715H
• Product Overview: Recombinant Human TREM2 (Accession # NP_061838), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc
• Predicted N Terminal: His19
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind fluorescein-conjugated E. coli Bioparticles.The ED50 for this effect is typically 0.04 - 0.16 µg/mL.
• Molecular Mass: Recombinant Human TREM2, Fc Chimera has a calculated MW of 44 kDa (monomer). In SDS-PAGE migrates as 60-65 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: TREM2 triggering receptor expressed on myeloid cells 2 [ Homo sapiens ]
• Official Symbol: TREM2
• Synonyms: TREM2; triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2a; TREM 2; Trem2a; Trem2b; Trem2c; triggering receptor expressed on monocytes 2; TREM-2
• Gene ID: 54209
• mRNA Refseq: NM_018965
• Protein Refseq: NP_061838
• MIM: 605086
• UniProt ID: Q9NZC2
• Chromosome Location: 6p21.1