"CXCL12" Related Products

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Recombinant Human Stromal Cell-Dreived Factor 1, His-tagged

Cat. No.: CXCL12-64H
Product overview: Recombinant human SDF-1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography, 10.8 kDa (93aa)
Description: SDF-1 is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). SDF-1 is strongly chemotactic for lymphocytes andworks by its receptor CXCR4. The SDF-1+CXCR4 complex plays a significant role in the creation of metastases of neoplasms and as a response to cytostatic treatment. Identification of this complex may be a useful prognostic factor in the therapy of many types of carcinoma.
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MKPVSLSYRC PCRFFESHVA RANVKHLKIL NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKR FKM
Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Purity: > 90% by SDS - PAGE
Concentration: 0.5 mg/ml (determined by Bradford assay)
Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method )
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: CXCL12
Synonyms: PBSF; SCYB12; SDF-1a; SDF-1b; SDF1; SDF-1; SDF1A; SDF1B; TLSF; TLSF-a; TLSF-b; TPAR1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating factor; Stromal cell-derived factor 1 precursor; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); stromal cell-derived factor 1; stromal cell-derived factor 1 delta; stromal cell-derived factor 1 gamma; stromal cell-derived factor 1a; CXCL12.
Gene ID: 6387
mRNA Refseq: NM_199168
Protein Refseq: NP_954637
MIM: 600835
Uniprot ID: P48061
Chromosome Location: 10q11.1
Pathway: Axon guidance, Cytokine-cytokine receptor interaction, Leukocyte transendothelial migration
Function: chemokine activity, chemokine activity, growth factor activity, signal transducer activity

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