Recombinant Human MDM2, His6-HA-SUMO-tagged MDM2-110H

Recombinant Human MDM2, His6-HA-SUMO-tagged

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Recombinant Human MDM2, His6-HA-SUMO-tagged

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Cat.No. : MDM2-110H
Product Overview : Recombinant Human MDM2, fused with His6-HA-SUMO tag, was expressed in E.coli.
Source : E.coli
Species : Human
Tag : His6-HA-SUMO
Form : Liquid
Molecular Mass : 68kDa (with Tag)
AA Sequence : 1-491
Applications : Useful in conjunction with E1 and E2 for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage : Store at -80℃. Avoid repeated freeze/thaw cycles.
Gene Name : MDM2 Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) [ Homo sapiens ]
Official Symbol : MDM2
Synonyms : MDM2; Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse); Mdm2 p53 binding protein homolog (mouse) , Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) , mouse double minute 2, human homolog of; p53 binding protein; E3 ubiquitin-protein ligase Mdm2; HDM2; HDMX; MGC5370; oncoprotein Mdm2; MDM2 variant FB28; MDM2 variant FB30; double minute 2, human homolog of; p53-binding protein; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; hdm2; ACTFS; MGC71221;
Gene ID : 4193
mRNA Refseq : NM_002392
Protein Refseq : NP_002383
MIM : 164785
UniProt ID : Q00987
Chromosome Location : 12q13-q14
Pathway : AKT phosphorylates targets in the cytosol, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem;
Function : enzyme binding; ligase activity; metal ion binding; p53 binding; protein binding; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; zinc ion binding; zinc ion binding;

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