"MDM2" Related Products

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Recombinant Human MDM2, His6-HA-SUMO-tagged

Cat.No.: MDM2-110H
Product Overview: Recombinant Human MDM2, fused with His6-HA-SUMO tag, was expressed in E.coli.
Source: E.coli
Species: Human
Tag: His6-HA-SUMO
Form: Liquid
Molecular Mass: 68kDa (with Tag)
AA Sequence: 1-491
Applications: Useful in conjunction with E1 and E2 for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage: Store at -80℃. Avoid repeated freeze/thaw cycles.
Gene Name: MDM2 Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) [ Homo sapiens ]
Official Symbol: MDM2
Synonyms: MDM2; Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse); Mdm2 p53 binding protein homolog (mouse) , Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) , mouse double minute 2, human homolog of; p53 binding protein; E3 ubiquitin-protein ligase Mdm2; HDM2; HDMX; MGC5370; oncoprotein Mdm2; MDM2 variant FB28; MDM2 variant FB30; double minute 2, human homolog of; p53-binding protein; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; hdm2; ACTFS; MGC71221;
Gene ID: 4193
mRNA Refseq: NM_002392
Protein Refseq: NP_002383
MIM: 164785
UniProt ID: Q00987
Chromosome Location: 12q13-q14
Pathway: AKT phosphorylates targets in the cytosol, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem;
Function: enzyme binding; ligase activity; metal ion binding; p53 binding; protein binding; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; zinc ion binding; zinc ion binding;

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