Recombinant Human UBE2C UBE2C-118H

Recombinant Human UBE2C

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Recombinant Human UBE2C

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Cat.No. : UBE2C-118H
Product Overview : Recombinant Human UBE2C was expressed in E.coli.
Source : E.coli
Species : Human
Form : Liquid, 25 mM Tris, pH 7.4; 150 mM NaCl; 10 mM DTT; 10% glycerol
Molecular Mass : 19,652.6 Da by MS (calculated 19,652.3)
Purity : >95% by RP-HPLC
Applications : Identify cognate E2/E3 pairsCharacterize upregulation/downregulation of E2 enzymesBuild poly-ubiquitin chainsCharacterize ubiquitin chain specificity of E2 enzymesAnalyze expression of E2 enzymes
Storage : Store at -80℃. Avoid repeated freeze/thaw cycles.
Gene Name : UBE2C ubiquitin-conjugating enzyme E2C [ Homo sapiens ]
Official Symbol : UBE2C
Synonyms : UBE2C; ubiquitin-conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; UBCH10; ubiquitin-protein ligase C; ubiquitin carrier protein C; ubiquitin carrier protein E2-C; cyclin-selective ubiquitin carrier protein; mitotic-specific ubiquitin-conjugating enzyme; dJ447F3.2;
Gene ID : 11065
mRNA Refseq : NM_007019
Protein Refseq : NP_008950
MIM : 605574
UniProt ID : O00762
Chromosome Location : 20q13.12
Pathway : APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem;
Function : ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding; ubiquitin-protein ligase activity; contributes_to ubiquitin-protein ligase activity;

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