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Recombinant Human UBE2C

Cat.No.: UBE2C-118H
Product Overview: Recombinant Human UBE2C was expressed in E.coli.
Source: E.coli
Species: Human
Form: Liquid, 25 mM Tris, pH 7.4; 150 mM NaCl; 10 mM DTT; 10% glycerol
Molecular Mass: 19,652.6 Da by MS (calculated 19,652.3)
Purity: >95% by RP-HPLC
Applications: Identify cognate E2/E3 pairsCharacterize upregulation/downregulation of E2 enzymesBuild poly-ubiquitin chainsCharacterize ubiquitin chain specificity of E2 enzymesAnalyze expression of E2 enzymes
Storage: Store at -80℃. Avoid repeated freeze/thaw cycles.
Gene Name: UBE2C ubiquitin-conjugating enzyme E2C [ Homo sapiens ]
Official Symbol: UBE2C
Synonyms: UBE2C; ubiquitin-conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; UBCH10; ubiquitin-protein ligase C; ubiquitin carrier protein C; ubiquitin carrier protein E2-C; cyclin-selective ubiquitin carrier protein; mitotic-specific ubiquitin-conjugating enzyme; dJ447F3.2;
Gene ID: 11065
mRNA Refseq: NM_007019
Protein Refseq: NP_008950
MIM: 605574
UniProt ID: O00762
Chromosome Location: 20q13.12
Pathway: APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem;
Function: ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding; ubiquitin-protein ligase activity; contributes_to ubiquitin-protein ligase activity;

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