Recombinant Human TNFRSF25, Fc-tagged, Biotinylated TNFRSF25-596H

Recombinant Human TNFRSF25, Fc-tagged, Biotinylated

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Recombinant Human TNFRSF25, Fc-tagged, Biotinylated

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Cat.No. : TNFRSF25-596H
Product Overview : The recombinant human DR3-Fc fusion is expressed as a 403 amino acid protein consisting of Gln25 - Gln199 region of DR3 (UniProt accession #Q93038) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions
Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule)
Bio-activity : Binds to its ligand human TL1A/TNFSF15 and blocks TL1A-mediated signaling activity including TL1A-induced apoptosis in human tumor cell line TF-1.
Molecular Mass : Calculated molecular mass (kDa): 44.5; Estimated by SDS-PAGE under reducing condition (kDa): 55-60
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the
Purity : >95% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : TNFRSF25 tumor necrosis factor receptor superfamily, member 25 [ Homo sapiens ]
Official Symbol : TNFRSF25
Synonyms : TNFRSF25; tumor necrosis factor receptor superfamily, member 25; TNFRSF12, tumor necrosis factor receptor superfamily, member 12 (translocating chain association membrane protein); tumor necrosis factor receptor superfamily member 25; APO 3; DDR3; DR3; LARD; TR3; TRAMP; WSL 1; WSL LR; protein WSL-1; death receptor beta; apoptosis inducing receptor; apoptosis-inducing receptor AIR; apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; death domain receptor 3 soluble form; lymphocyte-associated receptor of death; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); APO-3; WSL-1; WSL-LR; TNFRSF12;
Gene ID : 8718
mRNA Refseq : NM_001039664
Protein Refseq : NP_001034753
MIM : 603366
UniProt ID : Q93038
Chromosome Location : 1p36.2
Pathway : Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function : binding; receptor activity; tumor necrosis factor-activated receptor activity;

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