Recombinant Human FURIN protein, His-tagged


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Recombinant Human FURIN protein, His-tagged

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Cat.No. : FURIN-16H
Product Overview : Recombinant Human FURIN(Asp108-Glu715) fused with His tag at C-terminal was expressed in NS0.
Source : NS0
Species : Human
Tag : His
Predicted N Terminal : Asp108 & Asp131
Form : Supplied as a 0.2 μm filtered solution in Tris, CaCl2, NaCl, Brij-35 and Glycerol.
Bio-activity : Measured by its ability to cleave the fluorogenic peptide substrate pERTKR-AMC. The specific activity is >125 pmol/min/µg.
Molecular Mass : Predicted Molecular Mass: 67 kDa;
SDS-PAGE: 65-85 kDa, reducing conditions.
Endotoxin : <1.0 EU per 1 μg of the protein by the LAL method.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage : Avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
3 months, -20 to -70 centigrade under sterile conditions after opening.
Gene Name : FURIN furin (paired basic amino acid cleaving enzyme) [ Homo sapiens ]
Official Symbol : FURIN
Synonyms : FURIN; furin (paired basic amino acid cleaving enzyme); FUR, PACE, paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) , PCSK3; furin; SPC1; FES upstream region; dibasic processing enzyme; dibasic-processing enzyme; furin, membrane associated receptor protein; proprotein convertase subtilisin/kexin type 3; paired basic amino acid residue-cleaving enzyme; FUR; PACE; PCSK3;
Gene ID : 5045
mRNA Refseq : NM_002569
Protein Refseq : NP_002560
MIM : 136950
UniProt ID : P09958
Chromosome Location : 15q26.1
Pathway : Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, organism-specific biosystem; Glypican 3 network, organism-specific biosystem;
Function : endopeptidase activity; metal ion binding; nerve growth factor binding; peptidase activity; peptide binding; protease binding; serine-type endopeptidase activity; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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