"IRF1" Related Products

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Recombinant Human interferon regulatory factor 1, His-tagged

Cat. No. : IRF1-25H
Product Overview : Recombinant Human Interferon Regulatory Factor-1 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 134 amino acids (1-114) with a His Tag of 20 aa, and having a molecular mass of 15 kDa. The IRF-1 is purified by proprietary chromatographic techniques.
Description : IRF1, Interferon regulatory factor 1, is a member of the interferon regulatory transcription factor (IRF) family which regulates gene expression critical to immune response, hematopoiesis and proliferation. IRF-1 is a transcriptional activator for IFN-A, IFN-B, and IFN-G stimulated genes. IRF1 is also a tumor suppressor transcription factor inducing apoptosis of tumorigenic cell lines.
Source : Escherichia Coli.
Amino Acid Sequence : MGSSHHHHHH SSGLVPRGSH MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKHAAKHGWDINK DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN KGSSAVRVYR MLPP
Physical Appearance : Sterile Filtered colorless solution.
Purity : Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : 1 mg/ml in 20mM Tris pH-8 and 10% glycerol.
Storage : Liquid Interferon although stable at 10°Cfor 1 week, should be stored below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Gene Name : IRF1 interferon regulatory factor 1 [ Homo sapiens ]
Synonyms : IRF1; interferon regulatory factor 1; MAR; IRF-1; OTTHUMP00000198266; interferon regulatory factor-1
Gene ID : 3659
mRNA Refseq : NM_002198
Protein Refseq : NP_002189
MIM : 147575
UniProt ID : P10914
Chromosome Location : 5q23-q31
Function : sequence-specific DNA binding; transcription factor activity

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