Recombinant Human Beta-2-microglobulin

Cat. No.: B2M-81H
Product Overview: Recombinant Human beta-2-microglobulin produced inE.Coliis a non-glycosylated polypeptide chain having a molecular mass of 11.76kDa. The rHuB2M is purified by proprietary chromatographic techniques.
Description: Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells.
Source: Escherichia Coli.
Physical Appearance: Sterile Filtered clear solution.
Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Anion-exchange FPLC. (c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained.
Formulation: The sterile solution (1.1mg/ml) contains phosphate-buffered saline (pH 7.4) and 0.05% NaN3.
Dimers And Aggregates: Less than 1% as determined by silver stained SDS-PAGE gel analysis.
Endotoxin: The endotoxin is less than 0.1 ng/µg of rHuB2M.
Storage: The rHuB2M although stable at 4°Cfor 3 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Gene Name: B2M beta-2-microglobulin [ Homo sapiens ]
Synonyms: B2M; beta-2-microglobulin; Beta-2 microglob ulin form pI 5.3; beta-2-microglobin; beta chain of MHC class I molecules
Gene ID: 567
mRNA Refseq: NM_004048
Protein Refseq: NP_004039
UniProt ID: P61769
Chromosome Location: 15q21-q22.2
MIM: 109700
Pathway: Antigen processing and presentation; HIV Infection; Signaling in Immune system
Function: protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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