Recombinant Human Beta-2-microglobulin

• Cat.No.: B2M-81H
• Product Overview: Recombinant Human beta-2-microglobulin produced inE.Coliis a non-glycosylated polypeptide chain having a molecular mass of 11.76kDa. The rHuB2M is purified by proprietary chromatographic techniques.

Specification

• Cat. No.: B2M-81H
• Description: Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells.
• Source: Escherichia Coli.
• Physical Appearance: Sterile Filtered clear solution.
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Anion-exchange FPLC. (c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained.
• Formulation: The sterile solution (1.1mg/ml) contains phosphate-buffered saline (pH 7.4) and 0.05% NaN3.
• Dimers And Aggregates: Less than 1% as determined by silver stained SDS-PAGE gel analysis.
• Endotoxin: The endotoxin is less than 0.1 ng/µg of rHuB2M.
• Storage: The rHuB2M although stable at 4°Cfor 3 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: B2M beta-2-microglobulin [ Homo sapiens ]
• Synonyms: B2M; beta-2-microglobulin; Beta-2 microglob ulin form pI 5.3; beta-2-microglobin; beta chain of MHC class I molecules
• Gene ID: 567
• mRNA Refseq: NM_004048
• Protein Refseq: NP_004039
• UniProt ID: P61769
• Chromosome Location: 15q21-q22.2
• MIM: 109700
• Pathway: Antigen processing and presentation; HIV Infection; Signaling in Immune system
• Function: protein binding