Recombinant Human Chemokine (C-C motif) Ligand 3
Cat.No. : | CCL3-79H |
Product Overview : | Recombinant Human chemokine (C-C motif) ligand 3 G0S19-1 protein sequence (containing the signal peptide sequence, and the mature human Interleukin 4 sequence) was expressed in modifiedhuman 293 cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CCL3-79H |
Description : | Human Macrophage inflammatory protein-1alpha (MIP-1 alpha; MIP-1a) belongs to the chemokine family. Chemokines are small secreted molecules containing 4 conserved cysteine residues and 2 disulfide linkages. MIP-1 alpha is constitutively expressed from platelets and bone marrow CD34 progenitor cells. MIP-1 alpha expression can also be induced by bacteria or bacterial products such as LPS in monocyte/macrophages, dendritic cells, neutrophils, microglial cells and in activated B and T cells. |
Source : | Human 293 cells. |
Amino Acid Sequence : | ADTPTACCFSYT SRQIPQNFIAD YFETS SQCS KPGVIFL TKRSRQV CADPSE EW VQ KY VSDLELSA. |
Molecular Mass : | MIP-1 alpha migrates in SDS-PAGE at approximately 10 kDa. This compares with the predicted molecular mass of 7.4kDa. |
PI : | MIP-1 alpha migrates in 2D PAGE with an observed pI of 4.8. This compares with the predicted pI of 4.77. |
Purity : | >95%, as determined by SDS-PAGE and visualized by silver stain. |
Formulation : | When reconstituted in 0.5 ml sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose. |
Reconstitution : | It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial. Working concentrations of MIP-1 alpha should be less than 100ng/ml to avoid aggregation. |
Storage : | Lyophilized products should be stored at 2 to 8°C. Following reconstitution short-term storage at 4°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended. |
Gene Name : | CCL3 chemokine (C-C motif) ligand 3 [ Homo sapiens ] |
Synonyms : | CCL3; chemokine (C-C motif) ligand 3; G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3; LD78 alpha beta; small inducible cytokine A3 (homologous to mouse Mip-1a); G0/G1 switch regulatory protein 19-1; Macrophage inflammatory protein 1-alpha; SIS-beta; Tonsillar lymphocyte LD78 alpha protein; Small-inducible cytokine A3 |
Gene ID : | 6348 |
mRNA Refseq : | NM_002983 |
Protein Refseq : | NP_002974 |
MIM : | 182283 |
UniProt ID : | P10147 |
Chromosome Location : | 17q11-q21 |
Pathway : | Cytokine-cytokine receptor interaction; Chemokine signaling pathway; Toll-like receptor signaling pathway |
Function : | chemoattractant activity; chemokine activity; signal transducer activity |
Products Types
◆ Recombinant Protein | ||
Ccl3-171C | Active Recombinant Mouse Ccl3 Protein (69 aa) | +Inquiry |
Ccl3-76M | Active Recombinant Mouse Ccl3 Protein (Ala24-Ala92), N-His tagged, Animal-free, Carrier-free | +Inquiry |
CCL3-075C | Active Recombinant Human CCL3 Protein (69 aa) | +Inquiry |
CCL3-020H | Recombinant Human CCL3 Protein | +Inquiry |
Ccl3-8705M | Recombinant Mouse Ccl3 protein(Ala24-Ala92) | +Inquiry |
◆ Lysates | ||
CCL3-7723HCL | Recombinant Human CCL3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket