Recombinant Human Chemokine (C-X-C motif) Ligand 16

• Cat.No.: CXCL16-82H
• Product Overview: Recombinant Human chemokine (C-X-C motif) ligand 16 was expressed inE. Coli.

Specification

• Cat. No.: CXCL16-82H
• Description: Recombinant Human CXCL16 is a recently discovered alpha (CXC) chemokine which also has a characteristics of CC chemokines and a structure similar to Fractalkine. It may also play a role in attracting activated lymphocyte subsets during inflammation and may assist immune responses. Recombinant human CXCL16 is a 10.1kda protein containing 89 amino residues.
• Source: E. Coli.
• Note: If this material is not to be used for coating or labeling (or other applications requiring carrier free material), the addition of 0.1% BSA or HSA to dilution buffers or dilution in sterile culture media is recommended to enhance stability and minimize absorption to vial. Ideally, maintain stock >20ug/ml.
• Reactivity: Determined by its ability to chemoattract activated lymphocytes using a concentration range of 1.0-100.0 ng/ml.
• Purity: >95% by SDS-Page analysis. Endotoxin level is less than 0.1ng per ug (1EU/ug) of protein.
• Reconstitution: Lyophilized CXCL16 should be reconstituted in water to a concentration of 0.1-1mg/ml. Allow to set at least 30 minutes at 4 °C, mix well. If desired, tighten cap and centrifuge for 1 minute at 1000rpm to concentrate material in vial. This solution can be diluted into other buffered solutions or stored at 4 °C for up to 1 week or at -20 °C for future use.
• Storage: The lyophilized powder is stable at room temperature for a few weeks but it is best stored desiccated at -20 °C. Reconstituted CXCL16 should be stored in working aliquots at -20 °C. AVOID FREQUENT FREEZE THAW CYCLES.
• Sequence: NEGSVTGSCY CGKRISSDSP PSVQFMNRLRKHLRAYHRCL YY TR FQL LSW S VCGGNKDPWVQELMSCLDL KECGHAYSGI VAHQKHLLP.
• Supplied: Lyophilized powder with no additives.

Gene Information

• Gene Name: chemokine (C-X-C motif) ligand 16 [Homo sapiens]
• Synonyms: chemokine (C-X-C motif) ligand 16; SRPSOX; CXCLG16; SR-PSOX; CXCL16; CXC chemokine ligand 16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; Small-inducible cytokine B16; Transmembrane chemokine CXCL16
• Gene ID: 58191
• mRNA Refseq: NM_001100812
• Protein Refseq: NP_001094282
• MIM: 605398
• UniProt ID: Q9H2A7
• Chromosome Location: 17p13
• Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Signaling by GPCR
• Function: chemokine activity; low-density lipoprotein receptor activity; scavenger receptor activity