"NRTN" Related Products

Recombinant Human Neurturin

Cat. No.: NRTN-953H
Product Overview: Recombinant human Neurturin produced inE.Coliis a homodimeric 23.6 kDa protein consisting of two identical subunits each containing 103 amino acid residues.
Description: Human Neurturin (NTN) and human GDNF comprise a family of TGF-beta related neurotrophic factor which have trophic influences on a variety of neuronal populations. Neurturin promotes the survivability of certain sympathetic and sensory neurons through interaction with distinct set of GDNF-like receptors.
Source: E.Coli.
Purity: 98 % (SDS-PAGE, HPLC).
Endotoxin Level: < 0.1 ng per ug of Neurturin.
Stabilizer: None.
Formulation: Lyophilized.
Biological Activity: Human Neurturin is fully biologically active when compared to standards. Human Neurturin at a concentration of 50-100 ng/ml will support the survival of 65% of newborn rat sympathetic neurons.
Reconstitution: The lyophilized human Neurturin can be reconstituted in water to a concentration of 1 mg/ml. This solution can be diluted into other buffered solutions or stored at -20°C for future use. For most in vitro applications, Neurturin exerts its biological activity in the concentration of 0.1 to 10 ng/ml.
Stability: The lyophilized protein, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted Neurturin should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Pathways: Axon guidance
Gene Name: NRTN neurturin [ Homo sapiens ]
Synonyms: neurturin; NTN; NRTN
Gene ID: 4902
mRNA Refseq: NM_004558
Protein Refseq: NP_004549
MIM: 602018
UniProt ID: Q99748
Chromosome Location: 19p13.3
Function: growth factor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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