Active Recombinant Human FOS-like Antigen 1
Cat.No. : | FOSL1-1034H |
- Specification
- Gene Information
- Related Products
Cat. No. : | FOSL1-1034H |
Description : | The fos-related antigen 1 (Fra-1, or FosL1: Fos-like antigen 1) is a member of the Fos onco-protein family and a component of AP-1 transcription factor. Similar to other members of the family, Fra-1 contains a leucine zipper domain and a highly conserved C-terminal region. Transcription of Fra-1 gene is regulated by multiple cis-elements and 12-O-tetradecanoylphorbol-13-acetate (TPA). Fra-1 expression is associated with proliferation and invasiveness of breast cancer cells and other cancer cells. |
Source : | E. coli. |
Form : | Liquid. Supplied in 20 mM Tris-HCl pH 8.0, 20% glycerol, 100 mM KCl, 0.2 mM EDTA and 1 mM DTT. |
Purity : | > 95% by SDS-PAGE. |
Activity : | 20-200 ng are sufficient for an in vitro transcription assay and 100 ng are sufficient for a protein-protein interaction assay. |
Application : | Use only for research. FRA-1 can be applied in in vitro transcription assays, DNA-protein and protein-protein interaction assays. |
Usage : | For in vitro use only. |
Storage : | Quality guaranteed for 12 months store at - 80°C. Avoid freeze / thaw cycles |
Gene Name : | FOSL1 FOS-like antigen 1 [ Homo sapiens ] |
Synonyms : | FOSL1; FOS-like antigen 1; FRA; FRA1; fra-1; FOS-like antigen-1; Fos-related antigen; FRA-1 |
Gene ID : | 8061 |
mRNA Refseq : | NM_005438 |
Protein Refseq : | NP_005429 |
MIM : | 136515 |
UniProt ID : | P15407 |
Chromosome Location : | 11q13 |
Pathway : | Wnt signaling pathway |
Function : | protein dimerization activity; sequence-specific DNA binding; transcription activator activity; transcription factor activity |
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◆ Lysates | ||
FOSL1-6166HCL | Recombinant Human FOSL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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