||The fos-related antigen 1 (Fra-1, or FosL1: Fos-like antigen 1) is a member of the Fos onco-protein family and a component of AP-1 transcription factor. Similar to other members of the family, Fra-1 contains a leucine zipper domain and a highly conserved C-terminal region. Transcription of Fra-1 gene is regulated by multiple cis-elements and 12-O-tetradecanoylphorbol-13-acetate (TPA). Fra-1 expression is associated with proliferation and invasiveness of breast cancer cells and other cancer cells.
||Liquid. Supplied in 20 mM Tris-HCl pH 8.0, 20% glycerol, 100 mM KCl, 0.2 mM EDTA and 1 mM DTT.
||> 95% by SDS-PAGE.
||20-200 ng are sufficient for an in vitro transcription assay and 100 ng are sufficient for a protein-protein interaction assay.
||Use only for research. FRA-1 can be applied in in vitro transcription assays, DNA-protein and protein-protein interaction assays.
||For in vitro use only.
||Quality guaranteed for 12 months store at - 80°C. Avoid freeze / thaw cycles