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Recombinant Human FOSL1 Protein, GST-tagged

Cat.No. : FOSL1-4427H
Product Overview : Human FOSL1 full-length ORF ( AAH16648.1, 1 a.a. - 271 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
  • Related Products
Description : The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 55.44 kDa
AA Sequence : MFRDFGEPGPSSGNGGGYGGPAQPP AAAQAAQQKFHLVPSINTMSGSQEL QWMVQPHFLGPSSYPRPLTYPQYSP PQPRPGVIRALGPPPGVRRRPCEQI SPEEEERRRVRRERNKLAAAKCRNR RKELTDFLQAETDKLEDEKSGLQRE IEELQKQKERLELVLEAHRPICKIP EGAKEGDTGSTSGTSSPPAPCRPVP CISLSPGPVLEPEALHTPTLMTTPS LTPFTPSLVFTYPSTPEPCASAHRK SSSSSGDPSSDPLGSPTLLAL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FOSL1 FOS-like antigen 1 [ Homo sapiens ]
Official Symbol : FOSL1
Synonyms : FOSL1; FOS-like antigen 1; fos-related antigen 1; fra 1; FOS-like antigen-1; FRA; FRA1; fra-1;
Gene ID : 8061
mRNA Refseq : NM_005438
Protein Refseq : NP_005429
MIM : 136515
UniProt ID : P15407

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any ongoing studies investigating the role of FOSL1 in combination with other targeted therapies? 02/07/2022

Yes, preclinical studies and early-phase clinical trials are exploring the potential synergistic effects of combining FOSL1 inhibitors with other targeted therapies to enhance treatment efficacy.

How does the expression of FOSL1 correlate with patient survival in different cancers? 10/06/2021

High expression levels of FOSL1 have been associated with poor prognosis and shorter overall survival in various cancer patients.

How does the regulation of FOSL1 impact tumor microenvironment and metastasis? 05/06/2021

FOSL1 regulates the tumor microenvironment by promoting angiogenesis, immune evasion, and metastasis, thus contributing to cancer progression and spread.

What are the potential side effects of targeting FOSL1 in cancer treatment? 02/18/2017

Although the specific side effects may vary, common adverse effects of FOSL1-targeted therapies may include gastrointestinal disturbances, fatigue, and immunological reactions.

How does the dysregulation of FOSL1 contribute to tumorigenesis? 08/05/2016

Dysregulated FOSL1 expression can disrupt cellular homeostasis, leading to uncontrolled cell proliferation, evasion of cell death, and genomic instability, all of which contribute to tumorigenesis.

Customer Reviews (3)

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Reviews
09/22/2022

    This reliable supply chain management assures that I have uninterrupted access to the protein, allowing me to plan and conduct my experiments without concern for availability issues.

    05/27/2019

      They ensure a reliable and consistent supply of FOSL1 protein, minimizing any potential disruptions in my experimental workflow.

      07/07/2016

        They ensure a reliable and consistent supply of FOSL1 protein, minimizing any potential disruptions in my experimental workflow.

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