Recombinant Human FOSL1 Protein, GST-tagged
Cat.No. : | FOSL1-4427H |
Product Overview : | Human FOSL1 full-length ORF ( AAH16648.1, 1 a.a. - 271 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 55.44 kDa |
AA Sequence : | MFRDFGEPGPSSGNGGGYGGPAQPP AAAQAAQQKFHLVPSINTMSGSQEL QWMVQPHFLGPSSYPRPLTYPQYSP PQPRPGVIRALGPPPGVRRRPCEQI SPEEEERRRVRRERNKLAAAKCRNR RKELTDFLQAETDKLEDEKSGLQRE IEELQKQKERLELVLEAHRPICKIP EGAKEGDTGSTSGTSSPPAPCRPVP CISLSPGPVLEPEALHTPTLMTTPS LTPFTPSLVFTYPSTPEPCASAHRK SSSSSGDPSSDPLGSPTLLAL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | FOSL1 FOS-like antigen 1 [ Homo sapiens ] |
Official Symbol : | FOSL1 |
Synonyms : | FOSL1; FOS-like antigen 1; fos-related antigen 1; fra 1; FOS-like antigen-1; FRA; FRA1; fra-1; |
Gene ID : | 8061 |
mRNA Refseq : | NM_005438 |
Protein Refseq : | NP_005429 |
MIM : | 136515 |
UniProt ID : | P15407 |
Products Types
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◆ Lysates | ||
FOSL1-6166HCL | Recombinant Human FOSL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (5)
Ask a questionYes, preclinical studies and early-phase clinical trials are exploring the potential synergistic effects of combining FOSL1 inhibitors with other targeted therapies to enhance treatment efficacy.
High expression levels of FOSL1 have been associated with poor prognosis and shorter overall survival in various cancer patients.
FOSL1 regulates the tumor microenvironment by promoting angiogenesis, immune evasion, and metastasis, thus contributing to cancer progression and spread.
Although the specific side effects may vary, common adverse effects of FOSL1-targeted therapies may include gastrointestinal disturbances, fatigue, and immunological reactions.
Dysregulated FOSL1 expression can disrupt cellular homeostasis, leading to uncontrolled cell proliferation, evasion of cell death, and genomic instability, all of which contribute to tumorigenesis.
Customer Reviews (3)
Write a reviewThis reliable supply chain management assures that I have uninterrupted access to the protein, allowing me to plan and conduct my experiments without concern for availability issues.
They ensure a reliable and consistent supply of FOSL1 protein, minimizing any potential disruptions in my experimental workflow.
They ensure a reliable and consistent supply of FOSL1 protein, minimizing any potential disruptions in my experimental workflow.
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