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Recombinant Mouse Prion Protein, Globular Domain, His-tagged

Cat. No.: Prnp-1064M
Description: N-terminal His-tagged full-length prion protein (PrPc). The PrPc -like conformation of the protein after refolding procedure was confirmed by high resolution NMR spectroscopy. The native His tagged PrPc is the ideal tool for in vitro/in vivo investigations of the behaviour of cellular prions. It may be used for protein-protein interaction studies as well as for in vitro/in vivo conversion studies.
Source: E. coli.
Form: Liquid.Supplied in 10 mM sodium acetate pH 4.5 and 0.02 % sodium azide.
Purity: >95% by SDS-PAGE.
Usage: For in vitro use only.
Storage: Quality guaranteed for 12 months store at - 80°C. Avoid freeze / thaw cycles.
Gene Name: Prnp prion protein [ Mus musculus ]
Synonyms: Prnp; prion protein; PrP; PrPC; Sinc; CD230; PrPSc; Prn-i; Prn-p; PrP<C>; AA960666; AI325101; OTTMUSP00000015760
Gene ID: 19122
mRNA Refseq: NM_011170
Protein Refseq: NP_035300
UniProt ID: P04925
Chromosome Location: 2 75.0 cM
Pathway: Prion diseases
Function: copper ion binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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