Recombinant Human Interleukin 1 Family, Member 6, His-tagged

• Cat.No.: IL1F6-158H
• Product Overview: Recombinant Human IL1F6encoding the human IL1F6 (Met1-Phe158) was expressed inE.coli.It was recombined with a Hexa-his tag at the N-Terminus and purified by Ni-NTA column. MW=17.7 KD.

Specification

• Cat. No.: IL1F6-158H
• Description: IL-1F6 is a secreted cytokine that expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines.
• Sequence: Human IL1F6 (Met1–Phe158)1 MEKALKIDTP QQGSIQDINH RVWVLQDQTL IAVPRKDRMS PVTIALISCR HVETLEKDRG NPIYLGLNGL NLCLMCAKVG DQPTLQLKEK DIMDLYNQPE PVKSFLFYHS QSGRNSTFES VAFPGWFIAV SSEGGCPLIL TQELGKANTT DFGLTMLF 158
• Source: E.coli.
• Formulation: Lyophilized 100μg humanIL1F6 in 50μl of TBS (20mM Tris, 50mM NaCl, pH8.0). Carry free.
• Purity: >95% by SDS gel.
• Application: Cell biology.
• Reconstitution: Add 500μl deionized water to the vial to prepare a working stock solution at 200μg/mL. Allow to set at least 30 minutes at 4℃, mix well.
• Storage: Store lyophilized protein at -20℃ or -70℃. Lyophilized protein is stable for up to 6 months from date of receipt at -20℃ to -70℃. Upon reconstitution, this protein can be stored at -20℃ for a few weeks or at -70℃ in a manual defrost freezer for long term storage (six months). Aliquot reconstituted protein to avoid repeated freezing / thawing cycles.

Gene Information

• Gene Name: IL1F6 interleukin 1 family, member 6 (epsilon) [ Homo sapiens ]
• Synonyms: IL1F6; interleukin 1 family, member 6 (epsilon); FIL1; FIL1E; IL-1F6; MGC129552; MGC129553; IL1(EPSILON); FIL1(EPSILON); IL-1F6 (FIL-1-epsilon); interleukin 1, epsilon; Interleukin-1 family member 6; Interleukin-1 epsilon; IL-1 epsilon; FIL1 epsilon
• Gene ID: 27179
• mRNA Refseq: NM_014440
• Protein Refseq: NP_055255
• MIM: 605509
• UniProt ID: Q9UHA7
• Chromosome Location: 2q12-q14.1
• Function: cytokine activity; interleukin-1 receptor binding

Reviews

07/20/2022

When conducting experiments with HSP90AA1, clear and reliable interpretation of results can be obtained.

03/12/2021

The IL36A product has low endotoxin levels and does not interfere with experimental results.

08/12/2020

IL36A has important application value in the field of drug research and development, and has achieved certain research results.

Q&As

Does IL36A carry a fever risk?

In general, the use of IL36A does not cause significant fever reactions, but individual differences exist, if there are abnormalities, please consult a doctor.

How to prepare IL36A?

The IL36A is expressed, purified, and constructed using recombinant DNA technology in a suitable host expression system, usually through genetic engineering.

In what inflammatory diseases does recombinant IL36A have potential applications?

IL36A has potential application value in psoriasis, arthritis and other inflammatory diseases, but the specific efficacy needs further study.

Does IL36A have anti-tumor effects?

IL36A has been shown in some studies to have anti-proliferative and anti-invasive effects on certain tumors, but more studies are needed to confirm its specific mechanism of action and effect.

How is the research progress of IL36A?

The research of IL36A is progressing continuously, and some studies have shown its potential in immune regulation, anti-inflammatory effect and so on.

Can IL36A be used in animal experiments?

Yes, IL36A can be used in animal studies to investigate its mechanism of action and potential applications.