Pyrroline-5-carboxylate Reductase 1
Cat.No. : | CBCRY27 |
- Specification
- Gene Information
- Related Products
Cat. No. : | CBCRY27 |
Background : | Pyrroline-5-carboxylate reductase (P5CR) is a universal housekeeping enzyme that catalyzes the reduction of Delta(1)-pyrroline-5-carboxylate (P5C) to proline using NAD(P)H as the cofactor. The enzymatic cycle between P5C and proline is very important for the regulation of amino acid metabolism, intracellular redox potential, and apoptosis. |
Protein Classification : | Oxidoreductase |
Structure Weight : | 168155.50 Da |
Polymer : | 1 |
Molecule : | Pyrroline-5-carboxylate reductase 1 |
Chain Length : | 321 amino acids |
PDB ID : | 2GER |
MMDB ID : | 41542 |
Source : | E.coli |
Method : | X-Ray Diffraction |
Resolution : | 3.1Å |
Reference : | Meng, Z., Lou, Z., Liu, Z., Li, M., Zhao, X., Bartlam, M., Rao, Z. (2006) Crystal structure of human pyrroline-5-carboxylate reductase J.Mol.Biol. 359: 1364-1377 |
Gene Name : | PYCR1 |
Synonyms : | P5C; P5CR; PIG45; PP222; PYCR; P5C reductase; proliferation-inducing protein 45; pyrroline-5-carboxylate reductase 1; EC 1.5.1.2; P5C reductase 1; P5CR1 |
UniProt ID : | P32322 |
Gene ID : | 5831 |
Chromosome Location : | 17q25.3 |
Function : | binding; oxidoreductase activity; pyrroline-5-carboxylate resuctase activity |
Products Types
◆ Recombinant Protein | ||
Pycr1-5270M | Recombinant Mouse Pycr1 Protein, Myc/DDK-tagged | +Inquiry |
PYCR1-3175H | Recombinant Human PYCR1 Protein, MYC/DDK-tagged | +Inquiry |
PYCR1-1815H | Recombinant Human PYCR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PYCR1-3536R | Recombinant Rhesus Macaque PYCR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PYCR1-935H | Recombinant Human Pyrroline-5-carboxylate Reductase 1, His-tagged | +Inquiry |
◆ Lysates | ||
PYCR1-1448HCL | Recombinant Human PYCR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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