Interleukin-2 with its alpha Receptor

• Cat.No.: CBCRY33

Specification

• Cat. No.: CBCRY33
• Background: Interleukin-2 (IL-2) is an immunoregulatory cytokine that binds sequentially to the alpha (IL-2Ralpha), beta (IL-2Rbeta), and common gamma chain (gammac) receptor subunits.
• Protein Classification: Immune System
• Structure Weight: 40207.9 Da
• Polymer: 1
• Molecule: Interleukin-2
• Chain Length: 133 amino acids
• PDB ID: 1Z92
• MMDB ID: 33820
• Source: E.coli
• Method: X-Ray Diffraction
• Resolution: 2.80 Å
• Reference: Rickert, M., Wang, X., Boulanger, M.J., Goriatcheva, N., Garcia, K.C. (2005) The structure of interleukin-2 complexed with its alpha receptor. Science 308: 1477-1480

Gene Information

• Gene Name: IL2
• Synonyms: IL-2; TCGF; lymphokine; T cell growth factor; aldesleukin; interleukin-2; involved in regulation of T-cell clonal expansion; Aldesleukin
• UniProt ID: P60568
• Chromosome Location: 4q26-q27
• Function: cytokine activity; interleukin-2 receptor binding; protein binding; growth factor activity; kinase activator activity
• Gene ID: 3558