"IL2RA" Related Products


Interleukin-2 with its alpha Receptor

Cat. No.: CBCRY33
Background: Interleukin-2 (IL-2) is an immunoregulatory cytokine that binds sequentially to the alpha (IL-2Ralpha), beta (IL-2Rbeta), and common gamma chain (gammac) receptor subunits.
Protein Classification: Immune System
Structure Weight: 40207.9 Da
Polymer: 1
Molecule: Interleukin-2
Chain Length: 133 amino acids
PDB ID: 1Z92
MMDB ID: 33820
Source: E.coli
Method: X-Ray Diffraction
Resolution: 2.80 Å
Reference: Rickert, M., Wang, X., Boulanger, M.J., Goriatcheva, N., Garcia, K.C. (2005) The structure of interleukin-2 complexed with its alpha receptor. Science 308: 1477-1480
Gene Name: IL2
Synonyms: IL-2; TCGF; lymphokine; T cell growth factor; aldesleukin; interleukin-2; involved in regulation of T-cell clonal expansion; Aldesleukin
UniProt ID: P60568
Chromosome Location: 4q26-q27
Function: cytokine activity; interleukin-2 receptor binding; protein binding; growth factor activity; kinase activator activity
Gene ID: 3558

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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