Interleukin-2 with its alpha Receptor CBCRY33

Interleukin-2 with its alpha Receptor


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Interleukin-2 with its alpha Receptor

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Cat. No. : CBCRY33
Background : Interleukin-2 (IL-2) is an immunoregulatory cytokine that binds sequentially to the alpha (IL-2Ralpha), beta (IL-2Rbeta), and common gamma chain (gammac) receptor subunits.
Protein Classification : Immune System
Structure Weight : 40207.9 Da
Polymer : 1
Molecule : Interleukin-2
Chain Length : 133 amino acids
PDB ID : 1Z92
MMDB ID : 33820
Source : E.coli
Method : X-Ray Diffraction
Resolution : 2.80 Å
Reference : Rickert, M., Wang, X., Boulanger, M.J., Goriatcheva, N., Garcia, K.C. (2005) The structure of interleukin-2 complexed with its alpha receptor. Science 308: 1477-1480
Gene Name : IL2
Synonyms : IL-2; TCGF; lymphokine; T cell growth factor; aldesleukin; interleukin-2; involved in regulation of T-cell clonal expansion; Aldesleukin
UniProt ID : P60568
Chromosome Location : 4q26-q27
Function : cytokine activity; interleukin-2 receptor binding; protein binding; growth factor activity; kinase activator activity
Gene ID : 3558

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