Recombinant Human Calbindin 1, 28kDa CALB1-1393H

Recombinant Human Calbindin 1, 28kDa

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Recombinant Human Calbindin 1, 28kDa

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Cat. No. : CALB1-1393H
Product Overview : Recombinant human Calbindin1 was expressed inE.coliand purified by using conventional chromatography techniques. MW =30 kDa (261aa).
Description : Calbindin 1 is a calcium binding protein belonging to the troponin C superfamily. Calbindin is expressed in neural tissues. It plays an essential role in calcium regulation (including calcium transport and uptake, calcification of bone and teeth) and calcium related signalling in neurons and transiently in embryological development. This calbindin also has a role in protecting neurons from apoptotic cell death. Disregulation of this calbindin protein relates to epilepsy, amyotrophic lateral sclerosis, Huntington"s disease.
Source : E.coli.
Amino Acid Sequence : MAESHLQSSL ITASQFFEIW LHFDADGSGY LEGKELQNLI QELQQARKKA GLELSPEMKT FVDQYGQRDD GKIGIVELAH VLPTEENFLL LFRCQQLKSC EEFMKTWRKY DTDHSGFIET EELKNFLKDL LEKANKTVDD TKLAEYTDLM LKLFDSNNDG KLELTEMARL LPVQENFLLK FQGIKMCGKE FNKAFELYDQ DGNGYIDENE LDALLKDLCE KNKQDLDINN ITTYKKNIMA LSDGGKLYRT DLALILCAGD N
Form : Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol, 2mM EDTA.
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : CALB1 calbindin 1, 28kDa [ Homo sapiens ]
Synonyms : CALB1; calbindin 1, 28kDa; CALB; calbindin 1; RTVL-H protein; calbindin 1, (28kD); CAB27; D-28K; Calbindin D28; Vitamin D-dependent calcium-binding protein, avian-type; Calbindin
Gene ID : 793
mRNA Refseq : NM_004929
Protein Refseq : NP_004920
MIM : 114050
UniProt ID : P05937
Chromosome Location : 8p11
Function : calcium ion binding; protein binding; vitamin D binding

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