"IRAK2" Related Products


Recombinant Human IRAK2, GST-tagged, Active

Cat. No. : IRAK2-332H
Product Overview : Recombinant full-length human IRAK2 was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 103 kDa.
Description : Interleukin-1 receptor-associated kinase 2 (IRAK2) is important downstream signaling components of Toll-like receptors (TLRs). IRAKs were first described as signal transducers for IL-1 and later have been implicated in signal transduction of other members of the Toll/IL-1 receptor family. The interleukin-1 receptor (IL-1R) signaling pathway leads to NFκB activation in mammals. To date, four mammalian IRAKs have been identified (IRAK-1, IRAK-2, IRAK-4, and IRAK-M). It is believed that IRAK-2 could be an additional therapeutic target for inhibiting IL-1-induced inflammation.
Source : Sf9 insect cells using baculovirus.
Sequence : Full-length.
Applications : Kinase Assay, Western Blot.
Storage And Stability : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : IRAK2 interleukin-1 receptor-associated kinase 2 [ Homo sapiens ]
Synonyms : IRAK2; interleukin-1 receptor-associated kinase 2; IRAK-2; MGC150550;interleukin-1 receptor associated kinase-2; Interleukin-1 receptor-associated kinase-like 2
Gene ID : 3656
mRNA Refseq : NM_001570
Protein Refseq : NP_001561
MIM : 603304
UniProt ID : O43187
Chromosome Location : 3p25.3
Pathway : Apoptosis; Neurotrophin signaling pathway
Function : ATP binding; NF-kappaB-inducing kinase activity; protein heterodimerization activity; protein homodimerization activity; protein kinase activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.