"MAP4K5" Related Products

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Recombinant Human MAP4K5, GST-tagged, Active

Cat. No.: MAP4K5-341H
Product Overview: Recombinant full-length human KHS1 was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 135 kDa.
Description: KHS1 belongs to serine/threonine kinase family that has a STE20-like protein kinase domain which stimulates the stress-activated protein kinase (SAPK, also known as Jun kinase or JNK) pathway. It is a mitogen-activated protein kinase kinase kinase kinase 5, termed germinal center kinase related (GCKR). Recently, the KH domain of Escherichia coli polynucleotide phosphorylase has been reported to be necessary for autoregulation and growth at low temperature.
Source: Sf9 insect cells using baculovirus.
Sequence: Full-length.
Applications: Kinase Assay, Western Blot.
Storage And Stability: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 [ Homo sapiens ]
Synonyms: MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5; KHS; GCKR; KHS1; MAPKKKK5; germinal center kinase-related; kinase homologous to SPS1/STE20; EC 2.7.11.1;MAPK/ERK kinase kinase kinase 5; MEK kinase kinase 5; MEKKK 5
Gene ID: 11183
mRNA Refseq: NM_006575
Protein Refseq: NP_006566
MIM: 604923
UniProt ID: Q9Y4K4
Chromosome Location: 14q11.2-q21
Function: ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; small GTPase regulator activity; transferase activity

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